I want to began the month of July on a note that diversity is the basis for life. I can’t think of anything better to teach us about diversity, co-existence, and evolution than the fascinating Microbiome.
The microbiome affects us right from our birth till the end affecting our mental as well as physical health. The microbiome exhibits all sorts of differences in shape, size, color, metabolic functions in order to sustain life.
Much to learn from these tiny beings!!!!
Today’s Digest comprises of some interesting studies about effect of microbiome on chemotherapy and studies on tumor microbiome. It also includes articles exploring genetics of gut microbiome and the role of microbiome in inflammatory bowel disease. Additionally has a news article about taking microbiome therapies to clinical trials.
Hope you enjoy reading today’s digest!!
“Life on earth is such a good story you cannot afford to miss the beginning… Beneath our superficial differences we are all of us walking communities of bacteria. The world shimmers, a pointillist landscape made of tiny living beings”. – Lynn Margulis
Human Microbiota and Effectiveness of Cancer Chemotherapy – Shvets et al – Experimental Oncology
Immunity to commensal skin fungi promotes psoriasiform skin inflammation – Hurabielle et al – PNAS
Human Tumor microbiome
*Perspective: Probing the tumor micro(b)environment – Atreya et al – Science
Human Eye microbiome
Review: Current Knowledge on the Human Eye Microbiome: A Systematic Review of Available Amplicon and Metagenomic Sequencing Data – Delbeke et al – Acta Ophthalmologica
Human nearly-sterile sites (blood, organs, brain)
Blood Bacterial Profiles Associated with HIV Infection and Immune Recovery – Serranno-Villar et al – The Journal of Infectious Diseases
Human gut microbiome
*Genetics of human gut microbiome composition – Kurilshikov et al – bioRxiv
Review: The microbiome in inflammatory bowel diseases: from pathogenesis to therapy – Liu et al – Protein&Cell
Vertical Stratification in Urban Green Space Aerobiomes – Robinson et al – bioRxiv
Food and mood: how do diet and nutrition affect mental wellbeing? – Firth et al – BMJ
DRAM for distilling microbial metabolism to automate the curation of microbiome function – Shaffer et al – bioRxiv
MetaRibo-Seq measures translation in microbiomes – Fremin et al – Nature Communications
Microbes on the market
Enterome Secures €46M to Take Microbiome Therapies to Clinical Trials – Helen Albert – Labiotech.eu