May 8, 2023

Posted on May 7, 2023 by JP Cardenas

General and Human Microbiome

Microbial β-glucuronidases drive human periodontal disease etiology – Adam D Lietzan – Science Advances

Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling – Alicia R Berard – Cell Reports

Causal relationship between Gut Microbiota and Obstructive sleep apnea – Yi Wei – Archives of Gerontology and Geriatrics

Changes in the intestinal microbiota of children with hand, foot, and mouth disease under 3 years old – Su Yue Zhu – Medicine

Reduced microbial diversity of the nasopharyngeal microbiome in household contacts with latent tuberculosis infection – Cinthya Ruiz-Tagle – Scientific Reports

Pitfalls in sampling and analyzing low-biomass human nasal microbiome samples – Petra Pjevac – The Journal of Allergy and Clinical Immunology

The saga of non-traditional risk factors continues with proteomics, microbiome, ozone, ketone bodies, and depression: let us rethink prevention – Filippo Crea – European Heart Journal

Review: Stress, inflammation, microbiome and depression – Eva M Medina-Rodriguez – Pharmacology, Biochemistry, and Behavior

Review: Fungi and cancer – Aurelia Saftien – Gut

Review: L-Fucose is involved in human-gut microbiome interactions – Jungyeon Kim – Applied Microbiology and Biotechnology

Beneficial Microbes, Compounds and Interventions

Vitamin K2 supplementation improves impaired glycemic homeostasis and insulin sensitivity for type 2 diabetes through gut microbiome and fecal metabolites – Yuntao Zhang – BMC Medicine

Intermittent fasting alleviates non-alcoholic steatohepatitis by regulating bile acid metabolism and promoting fecal bile acid excretion in high-fat and high-cholesterol diet fed mice – Xiaozhuan Lin – Molecular Nutrition & Food Research

Animal Microbiome

Gut microbiome of mealworms (Tenebrio molitor Larvae) show similar responses to polystyrene and corn straw diets – Tursunay Mamtimin – Microbiome

Plant Microbiome

Review: The good, the bad, and the phosphate: regulation of beneficial and detrimental plant-microbe interactions by the plant phosphate status – Michael Paries – The New Phytologist

May 1, 2023

Posted on April 30, 2023 by JP Cardenas

Human and General Microbiome

Th17 cells sense microbiome to promote depressive-like behaviors – Eva M Medina-Rodriguez – Microbiome

Obese-associated gut microbes and derived phenolic metabolite as mediators of excessive motivation for food reward – Alice de Wouters d’Oplinter – Microbiome

Alteration of taste perception, food neophobia and oral microbiota composition in children with food allergy – Enza D’Auria – Scientific Reports

Translocating Lactobacillus torments tumors via tryptophan catabolism – Márcia S Pereira – Cell

Global trends in research related to the links between microbiota and antibiotics: a visualization study – Sa’ed H Zyoud – Scientific Reports

Modulation of antibiotic effects on microbial communities by resource competition – Daniel P Newton – Nature Communications

Review: Less is more: Antibiotics at the beginning of life – Martin Stocker – Nature Communications

Review: The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis – Ali Nabavi-Rad – Trends in Microbiology

Review: The orchestra of human bacteriome by hormones – Arif Luqman – Microbial Pathogenesis

Review: Targeting the human gut microbiome with small-molecule inhibitors – Amelia Y M Woo – Nature Reviews. Chemistry

Review: A precision environmental health approach to prevention of human disease – Andrea Baccarelli – Nature Communications

Review: Emerging role of bacterial outer membrane vesicle in gastrointestinal tract – Cheng-Mei Tian – Gut Pathogens

Review: The Gut Microbiota – Brain Axis: Potential Mechanism of Drug Addiction – Xiao Luo – Current Topics in Medicinal Chemistry

Beneficial Microbes and Compounds

The effects of live and pasteurized Akkermansia muciniphila on DSS-induced ulcerative colitis, gut microbiota, and metabolomics in mice – Liangyu Xue – Food & Function

Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium – Renan Oliveira Corrêa – Microbiome

Tumor-targeting engineered probiotic Escherichia coli Nissle 1917 inhibits colorectal tumorigenesis and modulates gut microbiota homeostasis in mice – Haibo Tang – Life Sciences

Animal Microbiome

Intestinal epigenotype of Atlantic salmon (Salmo salar) associates with tenacibaculosis and gut microbiota composition – Søren B Hansen – Genomics

Review: Environmental Effects on Bee Microbiota – Phuong N Nguyen – Microbial Ecology

Review: Illuminating the Oral Microbiome and its Host Interactions: Animal models of disease – George Hajishengallis – FEMS Microbiology Reviews

Plant Microbiome

Review: How does plant sex alter microbiota assembly in dioecious plants? – Qingxue Guo – Trends in Microbiology

Environmental Microbiome

Compositional Changes in Sediment Microbiota Are Associated with Seasonal Variation of the Water Column in High-Altitude Hyperarid Andean Lake Systems – Ignacio Ramos-Tapia – Microbiology Spectrum

Built Environment

Dynamics of microbial community composition during degradation of silks in burial environment – Bowen Wang – The Science of the Total Environment

Bioinformatics

DeepMicroGen: a generative adversarial network based method for longitudinal microbiome data imputation – Joung Min Choi – Bioinformatics

April 24, 2023

Posted on April 23, 2023 by JP Cardenas

Human and General Microbiome

Review: Effects of ultra-processed foods on the microbiota-gut-brain axis: The bread-and-butter issue – Zheyi Song – Food Research International

Review: The emerging role of the small intestinal microbiota in human health and disease – Renate Ruigrok – Gut Microbes

Gut microbiome can predict chemoradiotherapy efficacy in patients with esophageal squamous cell carcinoma – Takuma Sasaki – Esophagus

Multi-omics signatures in new-onset diabetes predict metabolic response to dietary inulin: findings from an observational study followed by an interventional trial – N Ďásková – Nutrition & Diabetes

Comparison of Conjunctival Sac Microbiome between Low and High Myopic Eyes – Kang Xiao – Journal of Microbiology

Sentinel or accomplice – gut microbiota and microglia cross-talk in disorders of gut-brain interaction – Haonan Zheng – Protein & Cell

Beneficial Microbes and Compounds

Effects of dietary fibers or probiotics on functional constipation symptoms and roles of gut microbiota: a double-blinded randomized placebo trial – Hao Lai – Gut Microbes

Review: Use of probiotic lactobacilli in the treatment of vaginal infections: In vitro and in vivo investigations – Peng Liu – Frontiers in Cellular and Infection Microbiology

Animal Microbiome

The hindgut microbiome contributes to host oxidative stress in postpartum dairy cows by affecting glutathione synthesis process – Fengfei Gu – Microbiome

Gut microbiome responds compositionally and functionally to the seasonal diet variations in wild gibbons – Qi Li – NPJ Biofilms and Microbiomes

Metagenomic and metatranscriptomic exploration of the Egyptian Red Sea sponge Theonella sp. associated microbial community – Manar El Samak – Marine Genomics

Vibrio cholerae Invasion Dynamics of the Chironomid Host Are Strongly Influenced by Aquatic Cell Density and Can Vary by Strain – Dianshu Zhao – Microbiology Spectrum

Antibiotic Conditioning Shapes Pseudosterile Mouse Models by Deleting Colonic Microbes Rather than Small Intestinal Microbes – Qingxue Chen – Microbiology Spectrum

Plant Microbiome

Microbiota-mediated nitrogen fixation and microhabitat homeostasis in aerial root-mucilage – Zhiqiang Pang – Microbiome

Metapangenomics of wild and cultivated banana microbiome reveals a plethora of host-associated protective functions – Simrandeep Singh – Environmental Microbiome

Effects of vermicompost leachate on nitrogen, phosphorus, and microbiome in a food waste bioponic system – Sumeth Wongkiew – Journal of Environmental Management

The effect of wheat genotype on the microbiome is more evident in roots and varies through time – Liliana Quiza – ISME Communications

Environmental Microbiome

Disentangling temporal associations in marine microbial networks – Ina Maria Deutschmann – Microbiome

Evaluating the Reproducibility of Amplicon Sequencing Data Derived from Deep-Sea Cold Seep Sediment-Associated Microbiota – Jie Kong – Microbiology Spectrum

Built Environment

BioMateriOME: to understand microbe-material interactions within sustainable, living architectures – Beatriz Delgado Corrales – Advances in Applied Microbiology

Microbiome Analysis: Protocols, Resources, Tools and Techniques

Deciphering associations between gut microbiota and clinical factors using microbial modules – Ran Wang – Bioinformatics

SituSeq: an offline protocol for rapid and remote Nanopore 16S rRNA amplicon sequence analysis – Jackie Zorz – ISME Communications

Integrating Multi-Omics Data to Construct Reliable Interconnected Models of Signaling, Gene Regulatory, and Metabolic Pathways – Krishna Kumar – Methods in Molecular Biology

Other

Interactions between the lipidome and genetic and environmental factors in autism – Chloe X Yap – Nature Medicine

December 30, 2022

Posted on December 30, 2022 by JP Cardenas

Happy New Year from the Microbiome Digest Team!

Human and General Microbiome

Microbiome Characteristics in Early Threatened Miscarriage Study (MCETMS): a study protocol for a prospective cohort investigation in China – Xiaofeng Chen – BMJ Open

Mapping the early life gut microbiome in neonates with critical congenital heart disease: multiomics insights and implications for host metabolic and immunological health – Yuan Huang – Microbiome

Metagenomic analysis reveals unexplored diversity of archaeal virome in the human gut – Ran Li – Nature Communications

Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis – Kristine Stø – Scientific Reports

Transition in vaginal Lactobacillus species during pregnancy and prediction of preterm birth in Korean women – Young-Ah You – Scientific Reports

Evaluating the ecological hypothesis: early life salivary microbiome assembly predicts dental caries in a longitudinal case-control study – Freida Blostein – Microbiome

Systematic Review: The effects of microbiota abundance on symptom severity in Parkinson’s disease: A systematic review – Eliša Papić – Frontiers in Aging Neuroscience

Systematic Review: A systematic review of microbiome-derived biomarkers for early colorectal cancer detection – Florine H Zwezerijnen-Jiwa – Neoplasia

Review: Current insights into skin lipids and their roles in cutaneous health and disease – Anna Nicolaou – Current Opinion in Clinical Nutrition and Metabolic Care

Beneficial Microbes and Compounds

Akkermansia supplementation reverses the tumor-promoting effect of the fecal microbiota transplantation in ovarian cancer – Zizhuo Wang – Cell Reports

Review: A novel approach to Lactiplantibacillus plantarum: From probiotic properties to the omics insights – Noemí Echegaray – Microbiological Research

Animal Microbiome

Prokaryotic and eukaryotic microbial communities associated with coral species have high host specificity in the South China Sea – Keke Cheng – The Science of the Total Environment

Assessing the causes and consequences of gut mycobiome variation in a wild population of the Seychelles warbler – Sarah F Worsley – Microbiome

Gut microbe Lactiplantibacillus plantarum undergoes different evolutionary trajectories between insects and mammals – Elisa Maritan – BMC Biology

Environmental Microbiome

Permafrost in the Cretaceous supergreenhouse – Juan Pedro Rodríguez-López – Nature Communications

Degradation pathways for organic matter of terrestrial origin are widespread and expressed in Arctic Ocean microbiomes – Thomas Grevesse – Microbiome

Temporary establishment of bacteria from indoor plant leaves and soil on human skin – Gwynne Á Mhuireach – Environmental Microbiome

Microbiome Analysis

Stochastic variational variable selection for high-dimensional microbiome data – Tung Dang – Microbiome

November 7, 2022

Posted on November 6, 2022 by JP Cardenas

Human and General Microbiome

Immunomodulatory fecal metabolites are associated with mortality in COVID-19 patients with respiratory failure – Matthew R Stutz – Nature Communications

Taxonomic Abundance in Primary and Secondary Root Canal Infections – Ronald Ordinola-Zapata – International Endodontic Journal

Review: The intestinal barrier in disorders of the central nervous system – Carolina Pellegrini – The Lancet. Gastroenterology & Hepatology

Review: Resistance is futile? Mucosal immune mechanisms in the context of microbial ecology and evolution – Emma Slack – Mucosal Immunology

Correspondence: A critical analysis of eating disorders and the gut microbiome – Sydney M Terry – Journal of Eating Disorders

Beneficial Microbes and Compounds

Bifidobacterial carbohydrate/nucleoside metabolism enhances oxidative phosphorylation in white adipose tissue to protect against diet-induced obesity – Gihyeon Kim – Microbiome

Lactobacillus rhamnosus GG supernatant promotes intestinal mucin production through regulating 5-HT4R and gut microbiota – Yu Gu – Food & Function

Animal Model Microbiome

Genetic and environmental circadian disruption induce weight gain through changes in the gut microbiome – Baraa Altaha – Molecular Metabolism

Strains producing different short-chain fatty acids alleviate DSS-induced ulcerative colitis by regulating intestinal microecology – Shuo Yang – Food & Function

Non-Model Animal Microbiome

Microbiome assembly and maintenance across the lifespan of bumble bee workers – Tobin J Hammer – Molecular Ecology

The gut microbiome reflects ancestry despite dietary shifts across a hybrid zone – Danny P Nielsen – Ecology Letters

Characterization of the core gut microbiota of Nile tilapia (Oreochromis niloticus): indication of a putative novel Cetobacterium species and analysis of its potential function on nutrition – Ziyue Zhang – Archives of Microbiology

Forensic Microbiome

Sampling from four geographically divergent young female populations demonstrates forensic geolocation potential in microbiomes – Thomas Clarke – Scientific Reports

Plant Microbiome

Insights into the potential for mutualistic and harmful host-microbe interactions affecting brown alga freshwater acclimation – Hetty KleinJan – Molecular Ecology

Built Environment Microbiome

Review: Microplastics in urban waters and its effects on microbial communities: a critical review – Saber Entezari – Environmental Science and Pollution Research International

Microbiome Analysis and Techniques

Assessing the Dark Field of Metaproteome – Haonan Duan – Analytical Chemistry

September 5, 2022

Posted on September 5, 2022 by JP Cardenas

Human and General Microbiome

Inflammatory bowel disease and cardiovascular diseases – Bing Chen – The American Journal of Medicine

Salivary microbiome in chronic kidney disease: what is its connection to diabetes, hypertension, and immunity? – Fengping Liu – Journal of Translational Medicine

Polymorphic microbes: a new emerging hallmark of cancer – Mark P Lythgoe – Trends in Microbiology

Does exposure to different types of menstrual protections affect the vaginal environment? – Nicolas Tessandier – Molecular Ecology

Gut commensal E. coli outer membrane proteins activate the host food digestive system through neural-immune communication – Shengya Geng – Cell Host & Microbe

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation – Mikal Jacob Hole – Hepatology

Beneficial Microbes and Compounds

The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice – Junyu Hao – Food & Function

Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota – Ata Ur Rehman – AMB Express

Animal Microbiome

Review: Comparative biology of germ-free and conventional poultry – A J Cowieson – Poultry Science

Freshwater mussels and host fish gut microbe community composition shifts after agricultural contaminant exposure – Stephanie P Gill – Journal of Applied Microbiology

September 3, 2022

Posted on September 3, 2022 by JP Cardenas

Highlights!!!

A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome – Shuqin Zeng – Nature Communications → Authors presented and described the main features of the Early-Life Gut Genomes (ELGG) catalog: a dataset of 32,277 genomes representing 2172 species from 6122 fecal metagenomes collected from children under 3-years old from different regions.

A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond – Brendon J Medley – The Journal of Biological Chemistry → AMUC_1438, a previously uncharacterized gene from A. muciniphila, encodes an O-glycopeptidase with mucin degrading capacity. This article shows relevant aspects of its enzymatic function.

Lactic acid from vaginal microbiota enhances cervicovaginal epithelial barrier integrity by promoting tight junction protein expression – David Jose Delgado-Diaz – Microbiome → metaproteomic analysis on vaginal swab samples and transcriptomics analysis of cervicovaginal epithelial cell cultures showed that lactic acid, a commonly produced metabolite by the vaginal lactobacilli, is capable of enhancing genital epithelial barrier integrity; this microbial feature may help prevent invasion by sexually transmitted pathogens.

Human and General Microbiome

Review: A Perspective of the Urinary Microbiome in Lower Urinary Tract Infections – A Review – Rigoberto Pallares-Mendez – Current Urology Reports

Review: Methanogenic archaea in the human gastrointestinal tract – Christoph Hoegenauer – Nature Reviews. Gastroenterology & Hepatology

Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes – Mark C Butcher – APMIS

Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure – Tatiana V Karpinets – BMC Cancer

Horizontal gene transfer enables programmable gene stability in synthetic microbiota – Teng Wang – Nature Chemical Biology

A Multiscale Spatiotemporal Model Including a Switch from Aerobic to Anaerobic Metabolism Reproduces Succession in the Early Infant Gut Microbiota – David M Versluis – mSystems

Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation – J Casper Swarte – Science Translational Medicine

Beneficial Microbes and Compounds

Intestinal Microbiomics and Metabolomics Insights into the Hepatoprotective Effects of Lactobacillus paracasei CCFM1222 Against the Acute Liver Injury in Mice – Weiling Guo – Probiotics and Antimicrobial Proteins

An Alternative Oat-Containing Ready-To-Use Therapeutic Food Does Not Alter Intestinal Permeability or the 16S rRNA Fecal Microbiome Configuration Among Children With Severe Malnutrition in Sierra Leone: A Randomized Controlled Trial – D Taylor Hendrixson – The Journal of Nutrition

Study on the Effect of Molecular Weight on the Gut Microbiota Fermentation Properties of Blackberry Polysaccharides In Vitro – Qiao-Yun Li – Journal of Agricultural and Food Chemistry

Animal Model Microbiome

Tissue-wide metabolomics reveals wide impact of gut microbiota on mice metabolite composition – Iman Zarei – Scientific Reports

Gut microbiota mediates the inhibition of lymphopoiesis in dietary-restricted mice by suppressing glycolysis – Si Tao – Gut Microbes

Non-Model Animal Microbiome

Limited microbiome differences in captive and semi-wild primate populations consuming similar diets – Sahana Kuthyar – FEMS Microbiology Ecology

Biodiversity, environmental drivers, and sustainability of the global deep-sea sponge microbiome – Kathrin Busch – Nature Communications

Strain-level profiling with picodroplet microfluidic cultivation reveals host-specific adaption of honeybee gut symbionts – Yujie Meng – Microbiome

Mucin O-glycan-microbiota axis orchestrates gut homeostasis in a diarrheal pig model – Bing Xia – Microbiome

Plant Microbiome

Stressful, isolated, yet diverse: Green roofs have rich microbiomes that are not dominated by oligotrophic taxa – Antoine Hénault – Environmental Microbiology Reports

Nodulation and nitrogen fixation in Medicago truncatula strongly alters the abundance of its root microbiota and subtly affects its structure – Andrzej Tkacz – Environmental Microbiology

Bioinformatic Tools and Microbiome Analysis Techniques

Gut bacterial nutrient preferences quantified in vivo – Xianfeng Zeng – Cell

Metric learning for comparing genomic data with triplet network – Zhi Ma – Briefings in Bioinformatics

STENSL: Microbial Source Tracking with ENvironment SeLection – Ulzee An – mSystems

Review: Emerging microfluidic technologies for microbiome research – Yue Yu – Frontiers in Microbiology

August 27, 2022

Posted on August 27, 2022 by JP Cardenas

Highlights!

Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation – Allison K Guitor – Microbiome → A survey of the microbiome from preterm infants showed that probiotics use during hospitalization of these infants reduced the diversity and prevented the persistence of antibiotic resistance genes in the gut microbiome. The authors used a targeted capture approach involving lower costs.

Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity – Fernando F Anhê – Gut → The exposition of mice to human gut microbiota after restrictive or malabsorptive bariatric surgery could improve glycaemic control, involving, for example, the inhibition of host sodium-glucose cotransporter (Sglt)-1.

Human and General Microbiome

Temporal dynamics of oropharyngeal microbiome among SARS-CoV-2 patients reveals continued dysbiosis even after Viral Clearance – Suman Kalyan Paine – NPJ Biofilms and Microbiomes

Comparison of Metagenomic Sequencing and the NanoString nCounter Analysis System for the Characterization of Bacterial and Viral Communities in Vaginal Samples – Todd N Wylie – mSphere

Oral Microbiota from Periodontitis Promote Oral Squamous Cell Carcinoma Development via γδ T Cell Activation – Wei Wei – mSystems

Gut Microbiota and Coronary Plaque Characteristics – Akihiro Nakajima – Journal of the American Heart Association

Toward FAIR Representations of Microbial Interactions – Alan R Pacheco – mSystems

Review: Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease – Baolei Jia – Trends in Microbiology

Review: Type 2 diabetes, gut microbiome, and systems biology: A novel perspective for a new era – Yoscelina Estrella Martínez-López – Gut Microbes

Beneficial Microbes and Compounds

Human gut bifidobacteria inhibit the growth of the opportunistic fungal pathogen Candida albicans – Liviana Ricci – FEMS Microbiology Ecology

Animal Model Microbiome

Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate – Isabel Huber-Ruano – Microbiome

Experimental methods modestly impact interpretation of the effect of environmental exposures on the larval zebrafish gut microbiome – Keaton Stagaman – Scientific Reports

A Metabologenomic approach reveals alterations in the gut microbiota of a mouse model of Alzheimer’s disease – Francesco Favero – PloS ONE

Non-Model Animal Microbiome

Intraintestinal Analysis of the Functional Activity of Microbiomes and Its Application to the Common Marmoset Intestine – Mika Uehara – mSystems

A comprehensive comparison of fecal microbiota in three ecological bird groups of raptors, waders, and waterfowl – Caiquan Zhao – Frontiers in Microbiology

IHNV Infection Induces Strong Mucosal Immunity and Changes of Microbiota in Trout Intestine – Zhenyu Huang – Viruses

Fungi and Soil Microbiome

Wildfire-dependent changes in soil microbiome diversity and function – Amelia R Nelson – Nature Microbiology

Fungal succession on the decomposition of three plant species from a Brazilian mangrove – Marta A Moitinho – Scientific Reports

Fungi-on-a-Chip: microfluidic platforms for single-cell studies on fungi – Felix Richter – FEMS Microbiology Reviews

Environmental Microbiome

Climate-Endangered Arctic Epishelf Lake Harbors Viral Assemblages with Distinct Genetic Repertoires – Myriam Labbé – Applied and Environmental Microbiology

Food Microbiome

Profiling of the microbiota in the remaining sports drink and orange juice in plastic bottles after direct drinking – Miho Kawachi – Journal of Oral Biosciences

Bioinformatic Tools and Microbiome Analysis Techniques

K-Clique Multiomics Framework: A Novel Protocol to Decipher the Role of Gut Microbiota Communities in Nutritional Intervention Trials – Carlo Mengucci – Metabolites

Principal microbial groups: compositional alternative to phylogenetic grouping of microbiome data – Aslı Boyraz – Briefings in Bioinformatics

Analysis of Gut Microbiome Using Fecal Samples – Ahmed Gamal – Methods in Molecular Biology

August 22, 2022

Posted on August 22, 2022 by JP Cardenas

Highlights!!

Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance – Jotham Suez – Cell → a randomized-controlled trial (120 healthy adults) observed the effects of saccharin, sucralose, aspartame, and stevia on the human microbiome showed person-specific, microbiome-dependent glycemic alterations. Saccharin and sucralose significantly impaired glycemic responses.

A comprehensive evaluation of microbial differential abundance analysis methods: current status and potential solutions – Lu Yang – Microbiome → assessment of several differential abundance analysis (DAA) tools, using real data-based simulations, suggests that “none of the evaluated methods is simultaneously robust, powerful, and flexible, which makes the selection of the best DAA tool difficult”. These findings suggest that the application of a DAA method depends of data context.

Systematic Review: Probiotics and Synbiotics Supplementation Improve Glycemic Control Parameters in Subjects with Prediabetes and Type 2 Diabetes Mellitus: A GRADE-assessed systematic review, meta-analysis, and meta-regression of randomized clinical trials – Kaveh Naseri – Pharmacological Research → “Our findings suggest that probiotic and synbiotic intake has favorable effects on glycemic profile in patients with prediabetes and T2DM.”

Human and General Microbiome

The diversity and abundance of gut microbiota are associated with the pain sensation threshold in the Japanese population – Yuki Takeuchi – Neurobiology of Disease

Oral microbiota associated with gingiva of healthy, gingivitis and periodontitis cases – Nemmat A Hussein – Microbial Pathogenesis

Effects of extracellular vesicles derived from oral bacteria on osteoclast differentiation and activation – Hyun Young Kim – Scientific Reports

Porphyromonas gingivalis is a risk factor for the development of nonalcoholic fatty liver disease via ferroptosis – Chao Yao – Microbes and Infection

Review: The Role of a Gut Microbial-Derived Metabolite, Trimethylamine N-Oxide (TMAO), in Neurological Disorders – Sankar Simla Praveenraj – Molecular Neurobiology

Review: The association between early-life gut microbiota and childhood respiratory diseases: a systematic review – Cristina Garcia-Maurino Alcazar – The Lancet. Microbe

Beneficial Microbes and Compounds

Effect of Bifidobacterium animalis subsp. lactis SF on enhancing the tumor suppression of irinotecan by regulating the intestinal flora – Zhongyue Ren – Pharmacological Research

Effect of probiotic supplementation on plasma metabolite profile after Roux-Y gastric bypass: a prospective, randomized, double-blind, placebo-controlled clinical trial – Marília Rizzon Zaparolli Ramos – International Journal of Obesity

Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis – Y Grace Cao – Cell Host & Microbe