July 14, 2021

General microbiome

Bacteriophage-Bacteria Interactions in the Gut: From Invertebrates to Mammals – Kirsch et al. – Annual Review of Virology

Helicobacter pylori infection has a detrimental impact on the efficacy of cancer immunotherapies – Oster et al. – Gut

Pregnancy and early life

Cervicovaginal microbiota and metabolome predict preterm birth risk in an ethnically diverse cohort – Flaviani et al. – JCI Insight

[REVIEW][Early-life gut microbiota and its connection to metabolic health in children: Perspective on ecological drivers and need for quantitative approach – Jian et al. – EBBioMedicine

Associations of air pollution and greenness with the nasal microbiota of healthy infants: A longitudinal study – Gisler et al. – Environmental Research

Human respiratory microbiome

Multi-omics profiling predicts allograft function after lung transplantation – Watzenböck et al. – European Respiratory Journal

Metagenomic Analysis Reveals A Possible Association Between Respiratory Infection and Periodontitis – Liu et al. – Genomics, Proteomics & Bioinformatics

Human skin microbiome

[REVIEW]Novel mechanisms of microbial crosstalk with skin innate immunity – Chinnappan & Harris-Tyron – Experimental Dermatology

Shifts in the skin bacterial and fungal communities of healthy children transitioning through puberty – Park et al. – Journal of Investigative Dermatology

Human gut microbiome

Gut-microbiota-targeted diets modulate human immune status – Wastyk et al. – Cell

[REVIEW]Silent hypoxia in COVID-19: a gut microbiota connection – Gopal et al. – Current Opinion in Physiology

[REVIEW]The Athlete and Gut Microbiome: Short-chain Fatty Acids as Potential Ergogenic Aids for Exercise and Training – Bongiovanni, Yin & Heaney

Identification and engraftment of new bacterial strains by shotgun metagenomic sequence analysis in patients with recurrent Clostridioides difficile infection before and after fecal microbiota transplantation and in healthy human subjects – Verma et al. – PLOS One

Kefir Ameliorates Specific Microbiota-Gut-Brain Axis Impairments in a Mouse Model Relevant to Autism Spectrum Disorder – van de Wouw et al. – Brain, Behavior, and Immunity

Animal microbiome

Comparative analysis of oral-gut microbiota between captive and wild long-tailed macaque in Thailand – Sawaswong et al. – Scientific Reports

Impact of the dietary inclusion of dried food residues on the apparent nutrient digestibility and the intestinal microbiota of dogs – Paßlack et al. – Archives of Animal Nutrition

Triphenyltin exposure causes changes in health-associated gut microbiome and metabolites in marine medaka – He et al. – Environmental Pollution

The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota – Bermudez-Martin et al. – Microbiome

Microbes in space

Seven years of Progress in Determining Fungal Diversity and Characterization of Fungi Isolated from the Japanese Experiment Module KIBO, International Space Station – Satoh et al. – Microbiology and Immunology

Food microbiology

[REVIEW]Virome studies of food production systems: time for ‘farm to fork’ analyses – Mahony & van Sinderen – Current Opinion in Biotechnology


D-MANOVA: fast distance-based multivariate analysis of variance for large-scale microbiome association studies – Chen & Zhang – Bioinformatics

Umibato: estimation of time-varying microbial interaction using continuous-time regression hidden Markov model – Hosoda, Fukunaga & Hamada – Bioinformatics

[PREPRINT]Stool Studies Don’t Pass the Sniff Test: A Systematic Review of Human Gut Microbiome Research Suggests Widespread Misuse of Machine Learning – Quinn – arXiv


Characterizing Microbiomes via Sequencing of Marker Loci: Techniques To Improve Throughput, Account for Cross-Contamination, and Reduce Cost – Harrison, Randolph & Buerkle – mSystems

Two-Target Quantitative PCR To Predict Library Composition for Shallow Shotgun Sequencing – Cho et al. – mSystems

Statistical approaches for differential expression analysis in metatranscriptomics – Zhang et al. – Bioinformatics

Benchmark of 16S rRNA gene amplicon sequencing using Japanese gut microbiome data from the V1–V2 and V3–V4 primer sets – Kameoka et al. – BMC Genomics

In vitro models of gut digestion across childhood: current developments, challenges and future trends – Fournier et al. – Biotechnology Advances

July 07, 2021

General microbiome

Cross-Scale Analyses of Animal and Human Gut Microbiome Assemblies from Metacommunity to Global Landscape – Ma – mSystems

Multi-site human microbiome

Microbiota long-term dynamics and prediction of acute graft-versus-host disease in pediatric allogeneic stem cell transplantation – Ingham et al. – Microbiome

Human gut microbiome

Early melanoma invasivity correlates with gut fungal and bacterial profiles – Vitali et al. – British Journal of Dermatology

The Interplay between fasting, gut microbiota, and lipid profile – Mohammadzadeh et al. – IJCP

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Effect of Differences in the Microbiome of Cyp17a1-Deficient Mice on Atherosclerotic Background – Künstner et al. – Cells

Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect – Beckmann et al. – Pharmacological Research

Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin – Suriano et al. – Microbiome

Animal microbiome (for animals in the wild)

Shades of grey: host phenotype dependent effect of urbanization on the bacterial microbiome of a wild mammal – Stothart & Newman – Animal Microbiome

Untargeted fecal metabolome analysis in obese dogs after weight loss achieved by feeding a high-fiber-high-protein diet – Bermudez Sanches et al. – Metabolomics

Water and extremophile microbiome (sea, rivers, lakes, glaciers, permafrost, high-salt)

Holocene life and microbiome profiling in ancient tropical Lake Chalco, Mexico – Moguel et al. – Scientific Reports


ORFograph: search for novel insecticidal protein genes in genomic and metagenomic assembly graphs – Dvorkina et al. – Microbiome


Measuring and mitigating PCR bias in microbiota datasets – Silverman et al. PLOS Computational Biology

May 05, 2021

Special Issue on Interplay of Gene Expression Regulation and Microbiome

Cells has a call for papers for a special issue about the ‘Interplay of Gene Expression Regulation and Microbiome‘. This Special Issue should serve as a platform to bring together recent advances in the understanding of the dynamic interplay between gene regulation and host-microbiome interaction.

Human oral microbiome

Anna Karenina and the subgingival microbiome associated with periodontitis – Altabtaei et al. – Microbiome

Human gut microbiome

[REVIEW]The Association Between Intestinal Bacteria and Allergic Diseases—Cause or Consequence? – Han et al. – Front. Cell. Infect. Microbiol.

[Review]Exploring the Modulatory Effects of Gut Microbiota in Anti-Cancer Therapy – Li, Deng & Chen – Front. Oncol.

[REVIEW]The interplay between Helicobacter pylori and gastrointestinal microbiota – Chen et al. Gut Microbes

Do Antibiotics Cause Obesity Through Long-term Alterations in the Gut Microbiome? A Review of Current Evidence – Vallianou et al. – Metabploism

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Gut microbiota contributes to the development of hypertension in a genetic mouse model of systemic lupus erythematosus – de la Visitación et al. – British Journal of Pharmacology

Infant gut microbiota modulation by human milk disaccharides in humanized microbiome mice – Rubio-Del-Campo – Gut Microbes

Animal microbiome (for animals in the wild)

Description and comparison of the skin and ear canal microbiota of non-allergic and allergic German shepherd dogs using next generation sequencing – Apostolopoulos et al. PLOS One


Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3 – Beghini et al. – eLife


Validation and standardization of DNA extraction and library construction methods for metagenomics-based human fecal microbiome measurements – Tourlousse et al. – Microbiome

April 28, 2021

General microbiome

Microbiota regulate innate immune signaling and protective immunity against cancer – Xing et al. – Cell Host & Microbe

Pregnancy and early life

[PREPRINT]Diet Potentially Drives the Differentiation of Eating Behaviours via Alterations to the Gut Microbiome in Infants – Yan et al. – bioRxiv

[REVIEW]Impact of Maternal Nutritional Supplementation during Pregnancy and Lactation on the Infant Gut or Breastmilk Microbiota: A Systematic Review – Zaidi, Moore & Okala – Nutrients

Infant Gut Microbiome Is Enriched with Bifidobacteria longumssp. infantisin Old Order Mennoniteswith Traditional Farming Lifestyle – Seppo et al. – Allergy

Human skin microbiome

Can antibiotic‐induced changes in the composition of the hair follicle microbiome regulate human hair growth? – Lousada et al. – Experimental Dermatology

Human gut microbiome

Multi-omics study reveals that statin therapy is associated with restoration of gut microbiota homeostasis and improvement in outcomes in patients with acute coronary syndrome – Hu et al. – Theranostics

Alteration of gut microbial profile in patients with diabetic nephropathy – Du et al. – Endocrine

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Sargassum fusiforme fucoidan modifies gut microbiota and intestinal metabolites during alleviation of hyperglycemia in type 2 diabetic mice – Wu et al. – Food & Function

Bidirectional interaction of nobiletin and gut microbiota in mice fed with a high-fat diet – Zhang et al. – Food & Function

Reshaping of the gastrointestinal microbiome alters atherosclerotic plaque inflammation resolution in mice – Garshick et al. – Scientif Reports

Animal microbiome (for animals in the wild)

Gut bacterial communities across 12 Ensifera (Orthoptera) at different feeding habits and its prediction for the insect with contrasting feeding habits – Zheng et al. – PLOS One

Impacts of radiation exposure on the bacterial and fungal microbiome of small mammals in the Chernobyl Exclusion Zone – Antwis et al. – Journal of Animal Ecology

Water and extremophile microbiome (sea, rivers, lakes, glaciers, permafrost, high-salt)

[PREPRINT]A Scenic River in Rural Ohio Shows Elevated Antibiotic Resistance Genes, Including Acinetobacter Tetracycline and Macrolide Resistance, Downstream of Wastewater Treatment Plant Effluent – Murphy et al. – bioRxiv

[PREPRINT]Diversity of free-living prokaryotes on terrestrial and marine Antarctic habitats – Bendia et al. – bioRxiv

The microbiome of the Black Sea water column analyzed by shotgun and genome centric metagenomics – Cabello-Yeves – Environmental Microbiome


Obtaining deeper insights into microbiome diversity using a simple method to block host and non‐targets in amplicon sequencing – Mayer et al. – Molecular Ecology Resources

April 21, 2021

General microbiome

Assessment of the microbiome during bacteriophage therapy in combination with systemic antibiotics to treat a case of staphylococcal device infection – Mu et al. – Microbiome

Pregnancy and early life

A Microbiota-Directed Food Intervention for Undernourished Children – Chen et al. – The New England Journal of Medicine

Bacterial-fungal interactions in the neonatal gut influence asthma outcomes later in life – Boutin et al. – eLife

Human vaginal microbiome

[REVIEW]The effect of different contraceptive methods on the vaginal microbiome – Bastianelli et al. – Expert Review of Clinical Pharmacology

Human gut microbiome and virome

The Gut Microbiome in Progressive Multiple Sclerosis – Cox et al. – Annals of Neurology

Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity – Zuo et al. – Microbiome

[REVIEW]The Gut Microbiome: a New Frontier in Musculoskeletal Research – Li et al. – Current Osteoporosis Reports

[REVIEW]Inflammation‐driven brain and gut barrier dysfunction in stress and mood disorders – Doney et al. – European Journal of Neuroscience

The gut microbiota is associated with clinical response to statin treatment in patients with coronary artery disease – Wang et al. – Atherosclerosis

[REVIEW]Dietary restrictions modulate the gut microbiota: Implications for health and disease – Schmidt and Lorentz – Nutrition Research

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Altering the microbiome inhibits tumorigenesis in a mouse model of oviductal high-grade serous carcinoma – Chen et al. – Cancer Research

Screening of probiotic candidates in a simulated piglet small intestine in vitro model – Hansen et al. – FEMS Microbiology Letters

Animal microbiome (for animals in the wild)

Microbiome reduction and endosymbiont gain from a switch in sea urchin life history – Carrier et al. – PNAS

[PREPRINT]Evidence that faecal carriage of resistant Escherichia coli by 16-week-old dogs in the United Kingdom is associated with raw feeding and that E. coli from these dogs are shared with humans and cause opportunistic infections – Mounsey et al. – bioRxiv

Diversity structure of the microbial communities in the guts of four neotropical termite species – Vikram et al. – PeerJ

Alteration of gut microbiota with a broad‐spectrum antibiotic does not impair maternal care in the European earwig – van Meyel et al. – Journal of Evolutionary Biology

Food microbiology

The effects of vegetable pickling conditions on the dynamics of microbiota and metabolites – Sawada et al. – PeerJ


[PREPRINT]Development of Microbiome Biomarkers for IgA: a Joint Modeling Approach – Sengupta et al. – bioRxiv

April 14, 2021

General microbiome

[REVIEW]The microbiome and human cancer – Sepich-Poore et al. – Science

[PERSPECTIVE]A framework for microbiome science in public health – Wilkinson et al. – Nature Medicine

A framework for microbiome science in public health –

Niche and local geography shape the pangenome of wastewater- and livestock-associated Enterobacteriaceae – Shaw et al. – Science Advances

Human gut microbiome

[REVIEW]Immune System, Microbiota, and Microbial Metabolites: The Unresolved Triad in Colorectal Cancer Microenvironment – Hanus et al. – Front. Immunol.

[REVIEW]Microbiome and colorectal cancer: A review of the past, present, and future – Johns & Petrelli – Surgical Oncology

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition – Colombo et al. – eLife

Intestinal microbiota drives cholestasis-induced specific hepatic gene expression patterns – Juanola et al.

Animal microbiome (for animals in the wild)

When your host shuts down: larval diapause impacts host-microbiome interactions in Nasonia vitripennis – Dittmer & Brucker – Microbiome

Plant, root, and soil microbiome

Gut microbiota-derived inosine from dietary barley leaf supplementation attenuates colitis through PPARγ signaling activation – Li et al. – Microbiome

Important ecophysiological roles of non-dominant Actinobacteria in plant residue decomposition, especially in less fertile soils – Bao et al. – Microbiome

Rhizosphere community selection reveals bacteria associated with reduced root disease – Yin et al. – Microbiome

Shotgun metagenomics reveals distinct functional diversity and metabolic capabilities between 12 000-year-old permafrost and active layers on Muot da Barba Peider (Swiss Alps) – Perez-Mon – Microbioal Genomics

Water and extremophile microbiome (sea, rivers, lakes, glaciers, permafrost, high-salt)

[PREPRINT]The Polar Night Shift: Annual Dynamics and Drivers of Microbial Community Structure in the Arctic Ocean – Wietz et al. – bioRxiv

Seafloor Incubation Experiment with Deep-Sea Hydrothermal Vent Fluid Reveals Effect of Pressure and Lag Time on Autotrophic Microbial Communities – Fortunato et al. – Environmental Microbiology


[PREPRINT]Plasmid fitness costs are caused by specific genetic conflicts – Hall et al. – bioRxiv


[PREPRINT]Comprehensive benchmarking of tools to identify phages in metagenomic shotgun sequencing data – Ho, Millard & van Schaik – bioRxiv

April 07, 2021

General microbiome

Primate phageomes are structured by superhost phylogeny and environment – Gogarten et al. – PNAS

Fungal‐induced glycolysis in macrophages promotes colon cancer by enhancing innate lymphoid cell secretion of IL‐22 – Zhu et al. – The EMBO Journal

A method for detection of SARS-CoV-2 RNA in healthy human stool: a validation study – Coryell et al. – The Lancet Microbe

The Ocular Microbiome and Microbiota and their Effects on Ocular Surface Pathophysiology and Disorders – Aragona et al. – Survey of Ophthalmology

Human oral microbiome

Multi-dimensional study of the oral microbiome, metabolite, and immunologic environment in peanut allergy – Ho et al. – Journal of Allergy and Clinical Immunology

Human skin microbiome

Temporal Variation in Staphylococcus aureus Protein A Genotypes from Nose and Skin in Atopic Dermatitis Patients – van Mierlo et al. – Dermatology

Sex‐Based Differences in Fecal Short‐Chain Fatty Acid and Gut Microbiota in Irritable Bowel Syndrome Patients – Sun et al. – Journal of Digestive Diseases

Human gut microbiome

[REVIEW]Ecological and evolutionary responses to antibiotic treatment in the human gut microbiota – Pennycook & Scanlan – FEMS Microbiology Reviews

Animal microbiome (for animals in the wild)

The Fecal and Serum Metabolomics of Giant Pandas Based on Untargeted Metabolomics – Yang et al. – Zoological Scienc

Microbes in space

Astrobiology of life on Earth – Hallsworth et al. – Environmental Microbiology
Mars’ surface is not universally biocidal – Hallsworth – Environmental Microbiology


Draft Genome Sequences and Antimicrobial Profiles of Three Staphylococcus epidermidis Strains from Neonatal Blood Samples – Afeke et al. – Microbiology Resource Announcements

CoCoNet: An Efficient Deep Learning Tool for Viral Metagenome Binning – Arisdakessian et al. – Bioinformatics


Rank normalization empowers a t-test for microbiome differential abundance analysis while controlling for false discoveries – Davis, Huang & Wang – Briefings in Bioinformatics

Discovering multiple types of DNA methylation from bacteria and microbiome using nanopore sequencing – Tourancheau et al. – Nature Methods

April 1, 2021

General microbiome

Viral genomic, metagenomic and human transcriptomic characterization and prediction of the clinical forms of COVID-19 – Rodrigez et al. – PLOS Pathogens

A multiomics approach to identify host-microbe alterations associated with infection severity in diabetic foot infections: a pilot study – Radzieta – et al. – NPJ Biofilms and Microbiomes

Pregnancy and early life

Interactions between gut microbiota and metabolites modulate cytokine network imbalances in women with unexplained miscarriage – Liu et al. – NPJ Biofilms and Microbiomes

Developmental trajectory of the healthy human gut microbiota during the first 5 years of life – Roswall et al. – Cell Host & Microbiome

Human gut microbiome

Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease – Toya et al. – PLOS One

Stool metabolome-microbiota evaluation among children and adolescents with obesity, overweight, and normal-weight using 1H NMR and 16S rRNA gene profiling – Jaimes et al. – PLOS One

Gut dysbiosis and mortality in hemodialysis patients – Lin et al. – NPJ Biofilms and Microbiomes

[REVIEW]The Interplay between Diet, Gut Microbes, and Host Epigenetics in Health and Disease – Shock et al. – The Journal of Nutritional Biochemistry

[REVIEW]Circadian rhythms and the gut microbiome synchronize the host’s metabolic response to diet – Lopez et al. – Cell Metabolism

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

Meta-analysis identifies the effect of dietary multi-enzyme supplementation on gut health of pigs – Ramani et al. – Scientific Reports

Silicon-containing water intake confers antioxidant effect, gastrointestinal protection, and gut microbiota modulation in the rodents – Wu et al. – PLOS One

Animal microbiome (for animals in the wild)

[PREPRINT]16S rRNA Amplicon Sequencing of Bagworm Metisa plana Walker (Lepidoptera: Psychidae) – Ting et al. – bioRxiv

Water and extremophile microbiome (sea, rivers, lakes, glaciers, permafrost, high-salt)

Metagenomic analysis exploring taxonomic and functional diversity of bacterial communities of a Himalayan urban fresh water lake – Ahmad et al. – PLOS One

Geochemical and metagenomics study of a metal-rich, green-turquoise-coloured stream in the southern Swiss Alps – Buetti-Dinh – PLOS One

Phages and viruses

[REVIEW]The human virome: assembly, composition and host interactions – Liang & Bushman – Nature Reviews Microbiology

[PREPRINT]Diverse viruses carrying genes for microbial extremotolerance in the Atacama Desert hyperarid soil – Hwang et al. – bioRxiv


MCPdb: The bacterial microcompartment database – Ochoa et al. – PLOS One
[Twitter]97% identity cutoff applied on humans and related species – Matthew Hahn


Single strain control of microbial consortia – Fedorec et al. – Nature Communications

Microbes and Art

A Cultural Triumph: Microbiology Student Makes A Petri Dish Masterpiece – McCammon – npr

March 31, 2021

Pregnancy and early life

Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low- and middle-income countries – Sands et al. – Nature Microbiology

Human gut microbiome

The Gut Microbiome Is Altered in Postmenopausal Women With Osteoporosis and Osteopenia – Rettedal at al. – JBMR Plus
[Review]Ageing of the gut microbiome: potential influences on immune senescence and inflammageing – Conway & Duggal – Ageing Research Reviews

Human esophageal microbiome

Esophageal microbiome in active eosinophilic esophagitis and changes induced by different therapies – Laserna-Mendieta et al. – Scientific Reports

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

[PREPRINT]Establishment and Resilience of Transplanted Gut Microbiota in Aged Mice – Wang et al. – bioRxiv

Animal microbiome (for animals in the wild)

Termites Are Associated with External Species-Specific Bacterial Communities – Soukup et al. – Applied and Environmental Microbiology

Plant, root, and soil microbiome

Assessment of fungal diversity in soil rhizosphere associated with Rhazya stricta and some desert plants using metagenomics – Noor et al. – Archives of Microbiology

The temperature sensitivity of soil: microbial biodiversity, growth, and carbon mineralization – Wang et al. – The ISME Journal

Water and extremophile microbiome (sea, rivers, lakes, glaciers, permafrost, high-salt)

Recovery of freshwater microbial communities after extreme rain events is mediated by cyclic succession – Shabarova et al. – Nature Microbiology


Reduced metagenome sequencing for strain-resolution taxonomic profiles – Snipen et al. – Microbiome

March 24, 2021

Human gut microbiome

[OPINION]Targeting the Gut Microbiome to Mitigate Immunotherapy-Induced Colitis in Cancer – Chang et al – Trends in Cancer

Direct impact of commonly used dietary emulsifiers on human gut microbiota – Naimi et al. – Microbiome

Animal experiments (mouse/rat experiments, chickens/pigs on different diets)

[REVIEW]Establishing causality in Salmonella-microbiota-host interaction: The use of gnotobiotic mouse models and synthetic microbial communities – Stecher – International Journal of Medical Microbiology

Gut microbiota dysbiosis promotes age-related atrial fibrillation by lipopolysaccharide and glucose-induced activation of NLRP3-inflammasome – Zhang et al. – Cardiovascular Research

Animal microbiome (for animals in the wild)

Composition and structure of the skin microbiota of rorquals off the Eastern South Pacific – Toro et al. – FEMS Microbiology Ecology

Plant, root, and soil microbiome

[PREPRINT]Neural networks and extreme gradient boosting predict multiple thresholds and trajectories of microbial biodiversity responses due to browning – Fontaine et al. – bioRxiv

Comparative microbial antibiotic resistome between urban and deep forest environments – Zheng et al. – Environmental Microbiology Reports


[PREPRINT]Genomic characterization of three novel Desulfobacterota classes expand the metabolic and phylogenetic diversity of the Phylum – Murphy et al. – bioRxiv