Category Archives: Metagenomics & Bioinformatics

May 22, 2026

Posted on by

Gut microbiome

Network topology of the gut microbiome associates with metabolic health in obesity – Blanca Lacruz-Pleguezuelos – Nature Communications

High-resolution metagenomic characterization of gut microbiota composition and functional pathways in irritable bowel syndrome – Purnika Damindi Ranasinghe – Scientific Reports 

Animal Microbiome

Host Filtering Shapes the Soil–gut Microbiome Linkages in Pastoral Systems – Upulika Jayaneththi – Microbial Ecology

Oral Microbiome

Citizen-science reveals changes in the oral microbiome in Spain through age and lifestyle factors – Jesse R. Willis – npj Biofilms and Microbiomes

Water Microbiome

Co-migration of hundreds of microbial species over metres drives selection and promotes non-motile hitchhikers – Susanna R. Grigson – Nature Communications

Soil Microbiome

Soil microbes are the tiny bioengineers running Earth’s underground factory – Suzanne Hassan-Dalléac – Communications Earth & Environment

Plant Microbiome

Nitrogen Application Under Integrated Water–Fertilizer Management Regulates Rhizosphere Nitrogen Dynamics, Microbial Communities, and Maize Productivity – Mengqi Huang – Microbial Ecology

Bioinformatics

Cayman enables large-scale analysis of gut microbiome carbohydrate-active enzyme repertoires – Quinten R. Ducarmon – Nature Microbiology

Characterization of the first complete genome sequence of yellow fever virus (YFV) in Sierra Leone: Implications for public health – John Demby Sandi – PLoS Neglected Tropical Disease

May 8, 2026

Posted on by

See you next week at MVIF!

#MVIF 49 program is out! 🤩 Free registration: cassyni.com/s/mvif-49Highlights: 🇮🇱 Netta Barak 🇳🇬 Gandonu Selome Ruth⭐️ Sponsor spotlight by Dagmara Lewandowska #IntegraBiosciencesKeynote:🇩🇪 Georg ZellerTalks:🇲🇦 Suleiman Aminu🇨🇳 Hongbin Liu🇳🇱 Jiyang Chan

— Microbiome Virtual International Forum (@microbiomevif.bsky.social) 2026-04-30T09:34:17.767Z

Gut microbiome

Gut microbial diversity and inferred capacity to produce short-chain fatty acids are associated with acute stress reactivity in healthy adults – Thomas Karner – Neurobiology of Stress

In our new study at @univie.ac.at , gut microbiome composition was linked to stress reactivity. Higher microbial diversity and inferred butyrate-producing capacity were associated with stronger cortisol reactivity, which may reflect a more adaptive response. 🧠🦠

— Thomas Karner (@thomaskarner.bsky.social) 2026-04-22T15:08:33.422Z

Non-concussive head impacts sustained during American football correlate with changes in gut microbiome diversity and composition – Zachary J. Pelland – PlosOne

Gut microbiome is associated with recurrence-free survival in patients with resected high-risk melanoma receiving adjuvant immune checkpoint blockade – Mykhaylo Usyk – Cell

Genome-wide sweeps create ecological units in the human gut microbiome – Xiaoqian Annie Yu – Nature

Gut microbiome features associated with Bifidobacterium colonization predict personalized probiotic persistence patterns – Tarini Shankar Ghosh – Nature Communications

Biogeography-associated emergence of enhanced oxygen tolerance in the abundant human gut commensal Segatella copri – Youssef El Mouali – Cell Host & Microbe 

Review: The impact of artificial sweeteners on bacterial physiology and the microbiome – Ciaram Staber – Trends in Microbiology 

Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition – Serena Boscaini – Nature Communications

If you missed it earlier this week check out the video on new research led by APC's @jfcryan.bsky.social & @moloneyger.bsky.social where they reveal for the first time how #coffee influences communication between the gut and the brain. buff.ly/x884r4f #GutBrainAxis #Microbiome #CoffeeScience

— APC Microbiome Ireland (@apcmicrobiomeirel.bsky.social) 2026-04-24T12:54:33.975Z

Urinary microbiome

Fatty acid auxotrophy as driver of Lactobacillus symbiosis in the female urinary tract – Michael L. Neugent – BioRxiv

Oral microbiome

Integrative host–microbiome modeling uncovers the implication of oral–gut translocation in advanced cirrhosis – Yi Jin – iMeta

Strain-level translocation and enrichment dynamics of oral bacteria in the lower gastrointestinal tract of stunted children – Simon Yersin – Gut Microbes

📢 new paper alert! 📢Do we find the same #bacteria in the mouth and in the gut of stunded children?Go find out: doi.org/10.1080/1949…#microbiome #gut #gutmicrobes #metagenomicWith @vonaeschlab.bsky.social at @dmf-unil.bsky.social

— Simon Yersin (@yersim.bsky.social) 2026-04-07T12:42:09.651Z

Plant microbiome

The Anna Karenina principle in the assembly of plant microbiome under pathogen stress – Da Li – npj Biofilms and Microbiomes

Bioinformatics

Evaluating Reference-Independent Pipelines for the Detection of Spreading Organisms in Metagenomic Datasets – Nikolay Sergeevich Popov – BioRxiv

Learning the Language of the Microbiome with Transformers – Neythen J Treloar – BioRxiv

Holobiont

Viewing ourselves as nature: Holobiont literacy influences nature connectedness – Jake M. Robinson – Ambio

What happens when people learn that humans are not standalone organisms, but walking ecosystems?Our new paper explored whether learning about the #holobiont concept – humans are symbiotic assemblages of a host & trillions of microbes – influences nature connectedness.1/

— Jake Robinson (@jake1.bsky.social) 2026-05-06T22:07:54.693Z

April 17,2026

Posted on by

See you next week at MVIF!

#MVIF 48 starts next week! Free registration: cassyni.com/s/mvif-48⭐️ Highlights:🇺🇸 Rachel R. Rock🇺🇸 @pamferretti.bsky.social ⭐️ Keynote:🇦🇺 @pam-engelberts.bsky.social and @jamesvolmer.bsky.social ⭐️ Talks: 🇨🇳 Linxing Chen🇨🇳 Zhemin Zhou🇦🇺 Hoai-An Nguyen

— Microbiome Virtual International Forum (@microbiomevif.bsky.social) 2026-04-13T11:02:11.436Z


Gut microbiome

Associations of the gut microbiome and cardiometabolic risk in adolescence: the HOME study – Jennifer L. Arzu – BMC Medical Genomics 

Insect Gut Microbiota as a Reservoir of Industrially Relevant Enzymes: A Comprehensive Review – Aswin Viswan – Microbial Ecology

Respiratory Microbiome

The commensal microbiome in respiratory tract tumors: From oncogenic mechanisms to clinical translation – Jiale Yu – Journal of Advanced Research

Bacteria of the lung microbiome and health biomarkers in chronic airway disease: a systematic review and meta-analysis – Lucia Grassi – npj Biofilms Microbiomes

Animal Microbiome

Multi-omics revealed the effects of rumen to blood path on early lactation performance in transition dairy cows – Guangfu Tang – Microbiome

Spiroplasma Display an Intricate Continuum of Infection Heterogeneity and Persistence in Myrmica Ants – Diego Castillo Franco – Molecular Ecology

Oral Microbiome

Loss of salivary agglutinin induces changes in the salivary microbiome and accelerates development of oral cancer – Marcell Costa de Medeiros – Microbiome

Water Microbiome

Ecological water replenishment reshapes the river microbiome along an urban-rural gradient: Enhanced diversity but compromised stability – Hongyuan Tian – Journal of Hydrology: Regional Studies

Soil Microbiome

Reduced legacy precipitation decreases microbial community growth efficiency and alters soil organic carbon in a California grassland – Linnea K. Hernandez – Microbiome

Impact of microbial consortia and fertilization regimes on the soil microbiome in maize field trials – Nils Kleinbölting – Scientific Reports

Plant Microbiome

Phenotypic resistance profiles and resistome variations between endophytic and epiphytic bacteria in apple fruits – Denis Kiplimo – Environmental Microbiome

Plant spatial compartmentalization buffers bacteriome structure and function under antibiotic stress – Caryn Kgokonyane Lenonyane – Scientific Reports

Bioinformatics

Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trials – Tom Eilers – Scientific Reports

Predicted meta-omics: A potential solution to multi-omics data scarcity in microbiome studies – Bianca-Maria Cosma – PLOS One

Genomic characterization of Comamonas kerstersii isolated from diarrheal patients in Bangladesh – Noshin Ibnat Rib – PLOS One

I had the joy of giving a kindergarten workshop: “Bacteria in and around us!” 🦠✨To spark their imagination and start our discussion, I showed them the beautiful @contamclub.bsky.social 2026 calendar, full of vividly colored and uniquely shaped bacterial colonies.1/3

— Svetlana Ugarcina Perovic (@svetlanaup.bsky.social) 2026-04-16T10:46:01.481Z

March 31,2026

Posted on by

Human Microbiome

The interplay between Peptostreptococcus and Fusobacterium as novel signatures in colorectal cancer recurrence – Yunhui Zhang – microbime

Dysbiosis of the nasal microbiome is associated with prospective acute exacerbation of COPD – Cristian Roca – microbiome

Water–vapor treatment of shower systems in healthcare facilities: reshaping built-environment microbiomes to improve Legionella control and protect at-risk patients – Tian You – microbiome

Animal Microbiome

Limosilactobacillus reuteri enhances production performance and ovarian function via modulation of the gut-ovary axis in laying hens – Yanchao Geng – microbiome

Heat stress suppresses lactation through potential rumen-mammary communication mediated by extracellular vesicles: integrated analysis of microbiome, metabolome, and miRNA profiles – Qi Huang – microbiome

Characterization of age-related changes in the gut microbiome and metabolome of Kunming dogs and their associations with police performance – Le Xu – microbiome

plant microbiome

Differential contributions of an antimicrobial effector from Verticillium dahliae to virulence and tomato microbiota assembly across natural soils – Wilko Punt – microbiome

Environmental & Data Microbiome

Microbiome Datahub: an open-access platform integrating environmental metadata, taxonomy, and functional annotation for comprehensive metagenome-assembled genome datasets – Hiroshi Mori – mi9crobiome

March 20, 2026

Posted on by

See you next week at MVIF!

See you next week at #MVIF 47! Heads up ⏰ due to daylight saving time, start times shift by 1 hour in some regions:1 hour earlier for Atlantic, 1 hour later for Pacific!

— Microbiome Virtual International Forum (@microbiomevif.bsky.social) 2026-03-16T09:09:52.170Z

Gut microbiome

Gut microbiota modulation via repeated donor fecal transplantation improves motor and gastrointestinal symptoms in drug-naïve Parkinson’s disease: a randomized phase 2 trial – Rui Zhang – Signal Transduction and Targeted Therapy 

Clinical Review: Advances in the pathophysiology, diagnosis, and management of celiac disease – John B Doyle – BMJ

Circulating gut microbial metabolites and risk of coronary heart disease: A prospective multi-stage metabolomics study – Yulu Zheng – Plos Medicine

Nasal microbiome

Composition and dynamics of the adult nasal microbiome – Cindy M. Liu – Microbiome

Respiratory tract microbiome

Mass azithromycin distribution and antibiotic resistance in the gut and nasopharynx: a cluster-randomized trial – Thuy Doan – Nature Medicine 

Animal microbiome

Microbial communities associated with two populations of the sponge Chondrilla nucula under present and projected climate conditions in the Aegean Sea – Gioti Anastasia – ARPHA Preprints

Comparative analysis of stress markers, metabolic health, and gut microbiota in healthy and disabled dogs in long-term shelters in Thailand – Adul Saengthong – Plos One

Priority effects drive strain-level community composition of honeybee gut microbiota – Aiswarya Prasad – The ISME Journal

Animal experiments

Estropausal gut microbiota transplant improves measures of ovarian function in adult mice – Minhoo Kim – Nature Aging 

Plant, root, soil microbiome

Breeding effects on the root-associated microbiome of Zea mays L. are linked to plant-induced variation in soil water potentials – Nicolas Tyborski – ISME Communications

🤩 Now out in @isme-microbes.bsky.social Comms!#NicolasTyborski and our wonderful #Rhizotraits team unravel how old landraces and modern varieties of maize distinctly modulate their #rhizosphere #microbiomes under drought via soil water potentials!🌽🥵🦠Thanks to #BayCEER #Rhizo4Bio #bmftr_bund

— Tillmann Lueders (@luederslab.bsky.social) 2026-03-19T14:42:21.506Z

Food microbiome

Leveraging publicly available datasets and machine learning approaches for predicting the health benefits of fermented foods – Elizabeth A. McDaniel – bioRxiv

Bioinformatics

MATRIX: Rapid Quantification of Total and Active Microbial Cells with Single Cell Phenotypes for Environmental Microbiomes – Milena Gonzalo – bioRxiv

So thrilled to share episode 2 of #MVIFconversations with you all!Getting to sit down with @bykriscampbell.bsky.social was such a privilege! If you're curious about where microbiome science is headed and why rigorous science communication matters more than ever, this one's for you.1/2

— Svetlana Ugarcina Perovic (@svetlanaup.bsky.social) 2026-02-24T09:48:59.589Z

March 19, 2026

Posted on by

Gut microbiome

Antibiotic use and gut microbiome composition links from individual-level prescription data of 14,979 individuals – Gabriel Baldanzi – Nature Medicine

Spatial transcriptomics maps host–gut microbiome biogeography at high resolution – Ioannis Ntekas – Nature Microbiology

Respiratory Microbiome

Empiric azithromycin alters the upper respiratory microbiome and resistome without anti-inflammatory benefit in COVID-19 – Abigail Glascock – Nature Microbiology

Dysbiosis of the nasal microbiome is associated with prospective acute exacerbation of COPD – Cristian Roca – Microbiome

Animal Microbiome

Towards standardization in pig microbiome research based on a comprehensive twenty-year review – Samuel Onyilokwu Enokela – Animal Microbiome

Longitudinal source-sink dynamics of fecal litter and farm indoor environmental resistomes in broiler chicken and Cherry Valley ducks – Peter Fauszt –  Animal Microbiome

Oral Microbiome

Denture-associated oral microbiome in dentate and edentulous older adults living in long-term care facilities – Muhammed Manzoor – Journal of Oral Microbiology

Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia – Jun Hyung Cha – Journal of Oral Microbiology

Water Microbiome

Water mass specific genes dominate the Southern Ocean microbiome – Emile Faure – Nature Communications

Plant Microbiome

Impacts of climate extremes on plant pathogens, microbiomes and plant health – Chao Xiong – Nature Reviews Microbiology

Heritability of the Pinus radiata root microbiome – Natalie Graham – Frontiers in Plant Science

Bioinformatics

DynaBiome: interpretable unsupervised learning of gut microbiome dysbiosis via temporal deep models – Awais Qureshi – BMC Bioinformatics

RP3Net: a deep learning model for predicting recombinant protein production in Escherichia coli – Evgeny Tankhilevich – Bioinformatics

MetaFX: feature extraction from whole-genome metagenomic sequencing data – Artem Ivanov – Bioinformatics

March 3rd ,2026

Posted on by

Human Microbiome

Early risperidone exposure impairs cognitive function by perturbation of the gut microbiome and bile acids/tyrosine-PTP1B axis – Huaiyu Ye – microbiome

Human DNA levels in feces reflect gut inflammation and associate with presence of gut species in IBD patients across the age spectrum -Chiara Mazzoni – microbiome

Animal Microbiome

Probiotic efficacy of Bacillus amyloliquefaciens TL106 from Tibetan pigs in metabolic syndrome: modulation of gut microbiota and metabolic in sows and suckling piglets – Wangyuan Yao – microbiome

Enhancing the fiber degradation efficiency in dairy cattle rumen through engineered bacterial communities – Jiayi Zhang – microbiome

Gut T cell-microbiota crosstalk orchestrates antibacterial immunity and mucosal homeostasis in teleost – Ming Geng – microbiome

Plant Microbiome

Host-driven evolution shapes the polysaccharide utilization profiles of alga-associated Flavobacteriaceae – Guanjing Cai – microbiome

Ecology-guided Bacillus SynCom from a rice–duckweed core reveals division of labor for concurrent growth promotion and sheath blight suppression – Yingjie Song – microbiome

Mikania micrantha invasion restructures rhizosphere nitrogen cycling through enzyme activation, microbial recruitment, and allelopathic regulation – Ruonan Wang – microbiome

Marine and Aquatic Environmental Microbiome

Reconstruction of coral holobionts and elucidation of the causal relationships among symbiodiniaceae, bacteria, and coral through single-cell raman spectroscopy metabolomics – Yang Shu – microbiome

Unlocking the unexplored AMPSphere in marine rare species – Shen Fan – microbiome

Potential survival strategies of novel comammox and nitrite-oxidizing Nitrospira synthesizing osmoprotectants in a wastewater microbiome treating high-ammonia brackish landfill leachate – Shohei Yasuda – microbiome

Stress-induced enrichment of Pseudomonas sp. stimulates the adaptive response of Auxenochlorella pyrenoidosa and antibiotic-resistant proliferation -Qian Liu – microbiome

Built Environment and Cultural Heritage Microbiome

Unraveling the microbiomes contributing to biodeterioration dynamics of limestone heritage at the Longmen Grottoes archeological site – Xiaoying Zhang – microbiome

February 13, 2026

Posted on by

Gut microbiome

Host factors dictate gut microbiome alterations in chronic kidney disease more strongly than kidney function – H. Krukowski – Nature Microbiology

Baby-to-baby strain transmission shapes the developing gut microbiome – Liviana Ricci – Nature

Animal Microbiome

Microbiome by transcriptome interactions triggered by a switch to an alternative diet in Nellore cattle – Anna Carolina Fernandes – Scientific Reports

Maternal supplementation with rumen-protected arginine reshapes the ileal microbiome and enhances neonatal lamb growth – Xiangjian Peng –  Animal Microbiome

Oral Microbiome

Stimuli-responsive, antimicrobial-loaded nanocarriers for oral biofilm control and microbiome restoration – Ding Chen – International Journal of Oral Science

Modulating the oral microbiome with dental biomaterials: A review of challenges, advances, and future perspectives – Woojin Choi – Biomaterials

Plant Microbiome

Large-scale multi-omics unveils host–microbiome interactions driving root development and nitrogen acquisition – Nannan Li – Nature Plants

Ecological composite fertilizer application enhances wheat yield and optimizes rhizosphere microbial community under reduced fertilization – Yu Wang – Frontiers in Plant Science

Bioinformatics

argNorm: normalization of antibiotic resistance gene annotations to the Antibiotic Resistance Ontology (ARO) – Svetlana Ugarcina Perovic – Bioinformatics

A negative binomial latent factor model for paired microbiome sequencing data – Hyotae Kim – BMC Bioinformatics

January 29, 2026

Posted on by

Animal microbiome

Host genetic background and environment have different effects on the establishment and structure of the adult worker honey bee gut microbiota – Breven Stark – PLOS ONE

Microbiota discovered in scorpion venom – Barbara Murdoch – PLOS ONE

Animal experiments / Disease models

Intestinal decontamination with rifaximin attenuates LSEC dysfunction and liver fibrosis in mice – Tingting Su – PLOS ONE

Periplaneta americana extract ameliorates recurrent oral ulcers in rats by enhancing the intestinal epithelial barrier and regulating gut microbiota – Kailing Li – PLOS ONE

Formononetin ameliorates SP-induced urticaria in mice via suppressing TAK1/MAK signaling pathway -Yan Wu –PLOS ONE

Lipopolysaccharide induced mouse depression model can better simulate changes in peripheral blood FFAs in alMDD -Jincai Pan –PLOS ONE

Human microbiome (gut & reproductive)

Stool and vaginal microbiome profiles patterns among Black and White endometrial cancer survivors: A pilot study in North Carolina – Mu Jin – PLOS ONE

Infection, immunity & host–microbe interactions

Examining the role of IgA in a persistent model of Staphylococcus aureus colonization – Yunys Perez-Betancourt – PLOS Pathogens

Diversify and conquer: How effector diversity is shaped by host–microbe co-evolution -Marion C Müller – PLOS Pathogens

Oo-No: Ophidiomyces ophidiicola–bacterial interactions and the role of skin lipids in development of ophidiomycosis – Jason W Dallas – PLOS Pathogens

Probiotics & food microbiology

In-vitro evaluation of probiotic potential of gut microbes isolated from retail chicken – Sangram Biswas – PLOS ONE

Antimicrobial resistance & clinical microbiology

Extended-spectrum β-lactamase and carbapenemase-producing Enterobacterales among adult patients and their family members at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia – Dessie Abera – PLOS ONE

Microbiome methods & bioinformatics

PCR bias impacts microbiome ecological analyses – Dharmik R Rathod – PLOS Computational Biology

CoSMIC: A hybrid approach for large-scale, high-resolution microbial profiling of novel niches – Maor Knafo – PLOS ONE

Environmental & applied microbiology

Developing a simple, cost-effective proof-of-concept vaccine candidate against EHEC for cattle – Cecilia M Duarte – PLOS ONE

Preventive effect of bentonite against pyoderma via direct binding capability of staphylococci – Mao Kaneki – PLOS ONE

Ultraviolet light and polyethylene glycol as environmental cleaning agents to reduce contamination of Pseudogymnoascus destructans in bat hibernacula – Alyssa J Stulberg – PLOS ONE

Water, pollution & human exposure

Micro- and nanoplastics in biological samples following a drinking water intervention in Barcelona, Spain – Emma Calikanzaros – PLOS Water

Human disease & biomarkers

Evidence of an allostatic response by intestinal tissues following induction of joint inflammation – Meghan M Moran – PLOS ONE

Multi-modal data to identify key factors influencing lung injury in ARDS patients undergoing invasive mechanical ventilation: A prospective multi-center observational study protocol – Zhimei Duan – PLOS ONE

Integrative genomic analysis reveals DHX58 as a key player in gastric cancer – Yan Li – PLOS ONE

Identifying biomarkers for diagnosis and disease activity monitoring in PSC-IBD and UC through proteomic profiling: A prospective study protocol – Ondrej Fabian – PLOS ONE

S100-alarmins, antenatal corticosteroids and the risk of late-onset sepsis in preterm infants – Gloria Kessler – PLOS ONE

Exploring the role of the key gene TNFAIP3 between periodontitis and influenza A through bioinformatic analysis and molecular docking – Mingxiang Xu – PLOS ONE

GC-MS based bioactive profiling of Phyllanthus niruri and its antibacterial potential – Zubair Khalid Labu – PLOS ONE

January 16, 2026

Posted on by

Human Microbiome

The testobolome in microbial testosterone metabolism and human health – Liisa Veerus –  
npj biofilms and microbiomes 

Multi-omic definition of metabolic obesity through adipose tissue–microbiome interactions – Rima M. Chakaroun – Nature Medicine

Gut microbiome

The microbiome at the centre of NAD+ supplementation – Youngjae Jo – Nature Metabolism

Meta-analysis of H. pylori and the gut microbiome interactions and clinical outcomes – Xiongjian Wu – Frontiers in Cellular and Infection Microbiology

Environmental Microbiome

High microbial diversity in glacial habitats uncoupled from the specialized microbiomes of resident chironomid fauna – Valeria Lencioni – PLOS One

Bacterial communities show distinctive spatial diversity patterns in productive truffle orchards amended with peat-based substrate – Pedro Marco –  Environmental Microbiome

Plant Microbiome

Root Triterpenoid Metabolites Drive the Assembly and Feedback Regulation of the Rhizosphere Microbiome During Flowering to Senescence in Rhododendron hybridum – Fei Shan – Frontiers in Microbiology

Drought-Tolerant Rhizobacterial Consortia Enhance Grapevine Growth and Tolerance to Water Deficit – Ginevra Canavera – Frontiers in Plant Science

Bioinformatics

Integrative analysis across metagenomic taxonomic classifiers: A case study of the gut microbiome in aging and longevity in the Integrative Longevity Omics Study – Tanya T. Karagiannis – PLOS Computational Biology

Novel artificial selection method improves function of simulated microbial communities – Bjorn Vessman – PLOS Computational Biology