Here’s your daily Digest. Highlights include an attempt to establish the causal link between gut microbiota and colorectal cancer in mice, an electric bandage to fight biofilm and antimicrobial resistance, and a group B Streptococcus vaccine that could save tens of thousands of babies per year.
General microbiology
Oral epithelial cells orchestrate innate type 17 responses to Candida albicans through the virulence factor candidalysin – Akash H. Verma et al. – Science Immunology
Methicillin Resistant Staphylococcus aureus Sequence Type (ST) 5 Isolates from Health Care and Agricultural Sources Adhere Equivalently to Human Keratinocytes – Samantha J. Hau et al. – Applied and Environmental Microbiology
Human gut microbiome
Human microbiome signatures of differential colorectal cancer drug metabolism – Leah Guthrie et al. – npj Biofilms and Microbiomes
Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial – Henrik Munch Roager et al. – Gut
Multi-site human microbiome
Review: Human microbiome, infections, and rheumatic disease – Ana Clara Camine et al. – Clinical Rheumatology
Review: The Microbiome and Bone and Joint Disease – Christopher J. Hernandez – Current Rheumatology Reports
Animal experiments
* Gavage of fecal samples from patients with colorectal cancer promotes intestinal carcinogenesis in germ-free and conventional mice – Sunny H. Wong and Liuyang Zhao – Gastroenterology
Animal microbiome
An integrative study on biologically recovered polyhydroxyalkanoates (PHAs) and simultaneous assessment of gut microbiome in yellow mealworm – Su Yean Ong et al. – Journal of Biotechnology
Plant, root and soil microbiome
Shifts in microbial communities in soil, rhizosphere and roots of two major crop systems under elevated CO2 and O3 – Peng Wang et al. – Scientific Reports
Year-round shotgun metagenomes reveal stable microbial communities in agricultural soils and novel ammonia oxidizers responding to fertilization – Luis H. Orellana et al. – Applied and Environmental Microbiology
Water and extremophile microbiome
High altitude, hyper-arid soils of the Central-Andes harbor mega-diverse communities of actinobacteria – Alan T. Bull et al. – Extremophiles
Sediment nitrogen cycling rates and microbial abundance along a submerged vegetation gradient in a eutrophic lake – Lu Yao et al. – Science of The Total Environment
Technology
* Electric Field Based Dressing Disrupts Mixed-Species Bacterial Biofilm Infection and Restores Functional Wound Healing – Barki, Kasturi Ganesh et al. – Annals of Surgery
Press: Study shows electric bandages can fight biofilm infection, antimicrobial resistance – MedicalXpress
Bioinformatics
Preprint: A novel multi SNP based method for the identification of subspecies and associated lineages and sub-lineages of the Mycobacterium tuberculosis complex by whole genome sequencing – Samuel I. W. Lipworth et al. – bioRxiv
Microbes in the news
Your Eyes Have Their Own Microbiome. Here’s What You Need To Do To Take Care Of It – Sam Berne – MBG Health
Does a Healthy Gut Equal a Long, Healthy Life? – Jim Pietrangelo – Healthline
Unlocking the Secrets of the Microbiome – Jane E. Brody – New York Times
Specific gut bacteria can help or hinder cancer treatments – Rich Haridy – New Atlas
Proprietary Prebiotic Fiber Tested in National Institutes of Health Pilot Study with End-Stage Renal Disease Patients – Kimberly J. Decker – Nutritional Outlook
Briny pool bacteria can clean up and power up – King Abdullah University of Science & Technology – EurekAlert
2 million Chinese mothers carry strep bacteria that can be fatal to newborns, study finds – Laurie Chen – South China Morning Post
* Vaccine for bacteria carried by 20% of pregnant women ‘could prevent 100,000 baby deaths’ – Sarah Boseley – The Irish Times
Research finds link between gut fungi, bacteria and obesity – Camille Bienvenu – Diabetes.co.uk
Microbes on the market
Microbiome Therapeutics prepares to launch ‘microbiome modulator’ – Stephen Daniells – NutraIngredients
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