Good Morning! This Monday’s digest includes research papers investigating microbiomes of nearly sterile sites, respiratory tract, oral cavity, gastric fluid and many with animal experiments and animal microbiomes. A review about gut microbiota and depression is also included. Happy readings!

General microbiome
Essay: Framing the discussion of microorganisms as a facet of social equity in human health – Ishaq et al. – PLOS ONE

Human respiratory microbiome
Airway microbiome composition correlates with lung function and arterial stiffness in an age-dependent manner – Lee et al. – PLOS ONE

Dysbiosis of lower respiratory tract microbiome are associated with inflammation and microbial function variety – Li et al. – BMC Respiratory Research

Human oral microbiome
Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis – Stehlikova et al. – MDPI Microorganisms

Human nearly-sterile sites
Molecular characterisation of the synovial fluid microbiome in rheumatoid arthritis patients and healthy control subjects – Mohsen Hammad et al. – PLOS ONE

Human gut microbiome
Helicobacter pylori antibody and pepsinogen testing for predicting gastric microbiome abundance – Choi et al. – PLOS ONE

Review: Gut‐microbiota‐brain axis in depression: The role of neuroinflammation – Carlessi et al. – European Journal of Neuroscience

Animal experiments
Effects of treatment with enrofloxacin or tulathromycin on fecal microbiota composition and genetic function of dairy calves – Foditsch et al. – PLOS ONE

Long-term high-grain diet altered the ruminal pH, fermentation, and composition and functions of the rumen bacterial community, leading to enhanced lactic acid production in Japanese Black beef cattle during fattening – Ogata et al. – PLOS ONE

CRISPR/Cas9-mediated gene deletion of the ompA gene in symbiotic Cedecea neteri impairs biofilm formation and reduces gut colonization of Aedes aegypti mosquitoes – Hegde et al. – PLOS ONE

Examining transmission of gut bacteria to preserved carcass via anal secretions in Nicrophorus defodiens – Miller et al. – PLOS ONE

Animal microbiome
California condor microbiomes: Bacterial variety and functional properties in captive-bred individuals – Jacobs et al. – PLOS ONE

Composition and structure of the culturable gut bacterial communities in Anopheles albimanus from Colombia – Galeano-Castaneda et al. – PLOS ONE

Estimating the degree to which distance and temperature differences drive changes in fish community composition over time in the upper Mississippi River – Larson et al. – PLOS ONE

Food microbiology
Resistome metagenomics from plate to farm: The resistome and microbial composition during food waste feeding and composting on a Vermont poultry farm – Eckstrom et al. – PLOS ONE

Bioturbation effect of fortified Daqu on microbial community and flavor metabolite in Chinese strong-flavor liquor brewing microecosystem – He et al. – Food Research International

Bioinformatics
Biomarker discovery in inflammatory bowel diseases using network-based feature selection – Abbas et al. – PLOS ONE

Techniques
Rapid, large-scale species discovery in hyperdiverse taxa using 1D MinION sequencing – Srivathsan et al. – BMC Biology

Today’s microbiome digest is very short and includes a few interesting articles. Enjoy reading.

General microbiome

Review: Cannabinoids and the Microbiota‐Gut‐Brain‐Axis: Emerging Effects of Cannabidiol and Potential Applications to Alcohol Use Disorders – Hollis C. Karoly – Alcoholism Clinical and Experimental Research

Review: The Microbiome Factor in Drug Discovery and Development– Andrea Nuzzo – Chemical Research in Toxicology

Human microbiome

The intestinal microbiome potentially affects thrombin generation in human subjects – Yassene Mohammed – Journal of thrombosis and haemostasis

Expert insights: The potential role of the gut microbiome‐bile acid‐brain axis in the development and progression of Alzheimer’s disease and hepatic encephalopathy – Wei Jia – Medicinal Research Reviews

The human oral cavity microbiota composition during acute tonsillitis: a cross-sectional survey – Yun Kit Yeoh – BMC Oral Health

Review: The microbiota-gut-brain axis: An emerging role for the epigenome – Tijs Louwies – Experimental Biology and Medicine

Animal microbiome / Animal experiments

Seven-day Green Tea Supplementation Revamps Gut Microbiome and Caecum/Skin Metabolome in Mice from Stress – Eun Sung Jung – Scientific Reports

The Mercury-Tolerant Microbiota of the Zooplankton Daphnia Aids in Host Survival and Maintains Fecundity under Mercury Stress – Jiunn C. Fong – Environmental Science & Technology

Plant microbiome

Successive passaging of a plant-associated microbiome reveals robust habitat and host genotype-dependent selection – Norma M. Morella – PNAS

Today’s microbiome digest includes several interesting reviews and perspectives mainly focusing on the role of human microbiome in allergic diseases, pancreatic health, aging, Cognitive Impairment, and IBS. Enjoy Saturday with the latest microbiome feed.

General microbiome

Mini review: Th9 cells in allergic diseases: a role for the microbiota?– Isabella Badolati – Scandavian of Immunology

Perspective: Microbiota in pancreatic health and disease: the next frontier in microbiome research – Ryan M. Thomas – Nature Reviews Gastroenterology & Hepatology

Review: Advancing functional and translational microbiome research using meta-omics approaches – Xu Zhang – Microbiome

Human microbiome

Perspective: The Unexplored World of Human Virome, Mycobiome, and Archaeome in Aging – Oscar Salvador Barrera-Vázquez – The Journals of Gerontology

Review: The Gut Microbiome as a Therapeutic Target for Cognitive Impairment – Yi Sun – The Journals of Gerontology

Relationship between the gut microbiome and energy/nutrient intake in a confined bioregenerative life support system (BLSS) – Juanjuan Chen – Applied and Environmental Microbiology

Brief report: Changes in gut microbial metagenomic pathways associated with clinical outcomes after the elimination of malabsorbed sugars in an IBS cohort – A. Mack – Gut microbes

Microbiota modification in hematology: still at the bench or ready for the bedside? – Christopher J. Severyn – Hematology Am Soc Hematol Educ Program

Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens– Samantha M. Ervin – Journal of Biological Chemistry

The role of gut microbiota for the activity of medicinal plants traditionally used in the European Union for gastrointestinal disorders – Timo A.Thumann – Journal of Ethnopharmacology

Review: Berry polyphenols metabolism and impact on human gut microbiota and health– Laura Lavefve – Food and Function

Association of suboptimal health status with intestinal microbiota in Chinese youths – Qi Sun – Journal of Cellular and Molecular Medicine

Animal microbiome / Animal experiments

Dominant and Subordinate Relationship Formed by Repeated Social Encounters Alters Gut Microbiota in Greater Long-Tailed Hamsters – Jidong Zhao – Microbial Ecology

Cattle intestinal microbiota shifts following Escherichia coli O157:H7 vaccination and colonizationtravel – Raies A. Mir – PLOS ONE

Characterization of the cecal microbiome composition of Wenchang chickens before and after fattening – Zhen Tan – PLOS ONE

Plant microbiome

Resource Announcement: Bacteriome and Mycobiome in Nicotiana tabacum Fields Affected by Black Shank Disease – Xiaoyulong Chen – Plant disease

Characterization and discrimination of microbial community and co‐occurrence patterns in fresh and strong flavor style flue‐cured tobacco leaves – Qianying Zhang – Microbiology Open

Microbiome news

MaaT Pharma Announces the Presentation of Positive Data with Its Lead Microbiome Biotherapeutic in Intestinal-Predominant Acute Graft-versus-Host-Disease at the ASH 2019 Annual Meeting

Good Morning! Highlights of today’s digest include investigation of microbial communities from ground water sources to develop bioremediation strategies for removal of contaminating micropollutants for production of drinking water, another study with whole-virome analysis identifies changes in the human gut virome in inflammatory bowl diseases with a hope to develop biomarkers and therapeutics. Also, take a look at cool techniques such as Photo-PCR with gold nanorods and irradiation that shortens time for cell lysis and termocycling allowing rapid detection of bacteria as a point-of-care diagnostic tool. Enjoy!

Human skin microbiome
Review: Revealing the secret life of skin With the microbiome you never walk alone – Sfriso et al. – International Journal of Cosmetic Science

Human urinary tract microbiome
ANTIBIOTIC EXPOSURE IN LONG-TERM CARE FACILITIES IS ASSOCIATED WITH URINARY MICROBIOME PERTURBATIONS – Schell et al. – Innovation in Aging

Human gut microbiome
In silico Identification of Riboswitches in the Human Gut Microbiome for
Therapeutic Applications – Kumari and Som – Journal of RNA and Genomics

Animal microbiome
Age, gut location and diet impact the gut microbiome of a tropical herbivorous surgeonfish – Parata et al. – FEMS Microbial Ecology

Microbial signatures of protected and impacted Northern Caribbean reefs: changes from Cuba to the Florida Keys – Weber et al. – Environmental Microbiology

Geographically isolated Colorado potato beetle mediating distinct defense responses in potato is associated with the alteration of gut microbiota – Wang et al. – Journal of Pest Science

Plant, root and soil microbiome
Dynamics of bacterial community in litter and soil along a chronosequence of Robinia pseudoacacia plantations – Xu et al. – Science of The Total Environment

Influence of invasion by Sosnowsky’s hogweed on nematode communities and microbial activity in forest and grassland ecosystems – Cerevkova et al. – Global Ecology and Conservation

Water and extremophile microbiome
*Exploring groundwater microbial communities for natural attenuation potential of micropollutants – Aldas-Vargas et al. – bioRxiv

Shifts in dimethylated sulfur concentrations and microbiome composition in the red-tide causing dinoflagellate Alexandrium minutum during a simulated marine heatwave – Deschaseaux et al. – Biogeosciences

Artificial light at night erases positive interactions across trophic levels – Maggi et al. – Functional Ecology

Review: Linking metagenomics to aquatic microbial ecology and biogeochemical cycles – Grossart et al. – Limnology and Oceanography

Anaerobic microbial communities can influence algal growth and nutrient removal from anaerobic digestate – Bankston and Higgins – Bioresource Technology

Analysis of microbial communities involved in organic matter and nitrogen removal in a full-scale moving bed biofilm reactor located near the Polar Arctic Circle – Rodriguez-Sanchez et al. – International Biodeterioration & Biodegradation

Enhanced volatile fatty acid production and microbial population analysis in anaerobic treatment of high strength wastewater – Lim et al. – Journal of Water Process Engineering

Rainfall Influences on Microbial Community Dynamics in an Urban Watershed – Banka et al. – Journal of Student-Scientists’ Research

Management of water bodies in show caves – A microbial approach – Moldovan et al. – Tourism Management

Built-environment
Continental-scale microbiome study reveals different environmental characteristics determining microbial richness and composition/quantity in hotel rooms – Fu et al. – bioRxiv

Food microbiology
Integrated Meta-omics Approaches To Understand the Microbiome of Spontaneous Fermentation of Traditional Chinese Pu-erh Tea – Zhao et al. – mSystems

Phages and viruses
*Whole-Virome Analysis Sheds Light on Viral Dark Matter in Inflammatory Bowel Disease – Clooney et al. – Cell Host & Microbe

Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study – Lindfors et al. – BMJ Gut

Bioinformatics
Detecting contamination in viromes using ViromeQC – Zolfo et al. – Nature Biotechnology

Review: Metagenomics: Is it a powerful tool to obtain lipases for application in biocatalysis? – Almeida et al. – Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics

Techniques
In-depth serum virome analysis in patients with acute liver failure with indeterminate etiology – Ren et al. – Archives of Virology

Visualization of viral infection dynamics in a unicellular eukaryote and quantification of viral production using VirusFISH – Castillo et al. – bioRxiv

High-efficiency multi-site genomic editing (HEMSE) of Pseudomonas putida through thermoinducible ssDNA recombineering – Aparicio et al. – bioRxiv

A user guide to environmental protistology: primers, metabarcoding, sequencing, and analyses – Geisen et al. – bioRxiv

MiniReview: Next-Generation Sequencing Coupled With in situ Hybridization: A Novel Diagnostic Platform to Investigate Swine Emerging Pathogens and New Variants of Endemic Viruses – Resende et al. – Frontiers in Veterinary Science

*Gold Nanorod-based Photo-PCR System for One-Step, Rapid Detection of Bacteria – Kim et al. – Nanotheranostics

Science career
Using a Systems Change Framework to Evaluate Academic Equity & Climate Efforts in a Graduate Program – Wallace and York – bioRxiv

Good Morning! Highlights of today’s digest include a promising probiotic effect of Lactobaccillus helveticus on acute liver failure as shown in an animal model study. Findings from another study about soil sterilization and how it leads to healthier soil microbiome and plant growth by modulating promotion of plant and beneficial microbes associations. Finally, check out an investigation aiming to generate a standardized approach for microbiome profiling by evaluating a series of hypervariable regions of 16S gene and estimating community richness across diverse sample types. Many review articles are also posted. Enjoy!

Pregnancy and early life

Acquisition and Development of the Extremely Preterm Infant Microbiota Across Multiple Anatomical Sites – Young et al. – J of Pediatric Gastroebterology and Nutrition

Multi-site human microbiome

Review: Urobiome: In Sickness and in Health – Wojciuk et al. – Microorganisms

Review: The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions – Ellis et al. – Microorganisms

Human oral microbiome

Analysis of the human oral microbiome from modern and historical samples with SPARSE and EToKi – Achtman and Zhou – bioRxiv

Human vaginal microbiome

HIV infection is associated with preterm delivery independent of vaginal microbiota in pregnant African women – Gudza-Mugabe et al. – The Journal of Infectious Diseases

Human gut microbiome

Review: Microbial Phenolic Metabolites: Which Molecules Actually Have an Effect on Human Health? – Marhuenda-Munoz et al. – Nutrients

Microbial succession during wheat bran fermentation and colonisation by human faecal microbiota as a result of niche diversification – Paepe et al. – ISME

Bifidogenic and butyrogenic effects of young barely leaf extract in an in vitro human colonic microbiota model – Sasaki et al. – AMB Express

Animal experiments

Dietary energy and protein levels influenced the growth performance, ruminal morphology and fermentation and microbial diversity of lambs – Cui et al. – Scientific Reports

*Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in d-galactosamine-treated rats – Wang et al. – Applied Microbiology and Biotechnology

Plant, root and soil microbiome

Evaluation of the ecological restoration of a coal mine dump by exploring the characteristics of microbial communities – Chen et al. – Applied Soil Ecology

*Soil sterilization leads to re-colonization of a healthier rhizosphere microbiome – Li et al. – Rhizosphere

Water and extremophile microbiome

Microbial composition and variability of natural marine planktonic and biofouling communities from the Bay of Bengal – Angelova et al. – Frontiers in Microbiology

Changes to the microbial communities within groundwater in response to a large crustal earthquake in Kumamoto, southern Japan – Morimura et al. – Journal of Hydrology

Increasing oxygen defciency changes rare and moderately abundant bacterial communities in coastal soft sediments – Sinkko et al. – Scientific Reports Nature Research

Probiotics / peribiotics

Review: Recent systems biology approaches for probiotics use in health aspects: a review – Yadave and Shukla – 3 Biotech

Bioinformatics

A phylogenetic model for the recruitment of species into microbial communities and application to studies of the human microbiome – Darcy et al. – bioRxiv

Developing a Reproducible Microbiome Data Analysis Pipeline Using the Amazon Web Services Cloud for a Cancer Research Group: Proof-of-Concept Study – Bai et al. – JMIR Medical Informatics

Techniques

*Evaluation of primer pairs for microbiome profiling across a food chain from soils to humans within the One Health framework – Wasimuddin et al. – bioRxiv

Rapid, selective and single cell electrical detection of antibiotic resistant bacteria – Kumar et al. – bioRxiv

Droplet Digital PCR Technology for Detection of Ilyonectria liriodendri from Grapevine Environmental Samples – Martinez Diz et al. – APS Publications

In today’s digest read about the Million Microbiome of Humans Project, problems in studies of the gut microbiome in Parkinson’s disease, and how bats’ gut bacteria are more closely tied to where bats live. Happy weekend!

Gut microbiome

*Review: Increasing Comparability and Utility of Gut Microbiome Studies in Parkinson’s Disease: A Systematic Review – Jeffrey M. Boertien – Journal of Parkinson’s Disease

Microbiome‐immune‐metabolic axis in the epidemic of childhood obesity: Evidence and opportunities – Halle J. Kincaid – Obesity Reviews

Vaginal microbiome

Cervicovaginal microbiome composition drives metabolic profiles in healthy pregnancy – Andrew Oliver – bioRxiv

Respiratory microbiome

Review: The microbiome of the upper respiratory tract in health and disease – Christina Kumpitsch – BMC Biology

Animal experiments

Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in d-galactosamine-treated rats – Qiangqiang Wang – Applied Microbiology and Biotechnology

Comparison of the fecal, cecal, and mucus microbiome in male and female mice after TNBS-induced colitis – Ariangela J. Kozik – PlosOne

Cranberry extracts promote growth of Bacteroidaceae and decrease abundance of Enterobacteriaceae in a human gut simulator model – Kathleen O’Connor – PlosOne

Animal microbiome

*Ecology and Host Identity Outweigh Evolutionary History in Shaping the Bat Microbiome – Holly L. Lutz – mSystems

High-throughput sequencing reveals the core gut microbiota of the mud crab (Scylla paramamosain) in different coastal regions of southern China – Hongling Wei – BMC Genomics

Probiotics

Production of multiple bacteriocins, including the novel bacteriocin gassericin M, by Lactobacillus gasseri LM19, a strain isolated from human milk – Enriqueta Garcia-Gutierrez – bioRxiv

Infected chronic ischemic wound topically treated with a multi-strain probiotic formulation: a novel tailored treatment strategy – Salvatore Venosi – Journal of Translational Medicine

Genomic and epidemiological evidence of bacterial transmission from probiotic capsule to blood in ICU patients – Idan Yelin – Nature Medicine

Water microbiome

Species-level microbiome composition of activated sludge – introducing the MiDAS 3 ecosystem-specific reference database and taxonomy – Marta Nierychlo – bioRxiv

Comparative microbial diversity across temperature gradients in hot springs from Yellowstone and Iceland – Peter T Podar – bioRxiv

Niche partitioning of microbial communities in riverine floodplains – Marc Peipoch – Scientific Reports

Biodegradability of wastewater determines microbial assembly mechanisms in full-scale wastewater treatment plants – Bing Zhang – Water Research

Techniques

Microfluidic cultivation and analysis tools for interaction studies of microbial co-cultures – Alina Burmeister and Alexander Grünberger – Current Opinion in Biotechnology

Selective culture enrichment and sequencing of feces to enhance detection of antimicrobial resistance genes in third-generation cephalosporin resistant Enterobacteriaceae – Leon Peto – PlosOne

Microbiome in News

*Million Microbiome of Humans Project – PRNewswire
Scientists from China, Sweden, Denmark, France, Latvia and other countries will cooperate in microbial metagenomic research, aiming to analyze one million microbial samples and build the world’s largest database of human microbiome.