July 31, 2026

Diet, Gut Health & Microbiome

Dietitian-led intervention to manage constipation in Parkinson’s disease: Study protocol for a parallel-group randomized controlled trial (NUTRI-GUT-PD) – Juliana Heitich Brendler – PLOS ONE

Efficacy and safety of prebiotics, probiotics, and synbiotics on hemoglobin and anemia in the pediatric population: A systematic review and meta-analysis – Gladys Estheysi Elías Solís – PLOS ONE

Pharmacokinetic model selection for infliximab based on inflammatory bowel disease phenotype and severity: Toward model-informed precision dosing – Ana Homšek Ilić – PLOS ONE

Pathogens, Infection & Host–Microbe Interactions

Neotropical bats as sentinels for emerging zoonoses in Central America: A case study identifying Trypanosoma cruzi in bats from Belize using metagenomic next-generation sequencing – Elissa G. Torgerson – PLOS Neglected Tropical Diseases

Viral replication dynamics: Coinfection and superinfection of Vero cells with Zika virus and West Nile virus or Zika virus and Mayaro virus – Larissa Krokovsky – PLOS ONE

Phenotypic and molecular characterization of Salmonella enterica isolated from retail beef in Peshawar, Pakistan – Muhammad Jawad Ullah – PLOS ONE

Longitudinal study of a rodent invasion reveals shifts in host pathogen interactions – Andrew McManus – PLOS ONE

Noncanonical bactericidal activity of teleost type I interferon is conferred by a membrane-targeting C-terminal peptide – Han Zhang – PLOS Pathogens

A single DNA methylation site regulates cell fate during Clostridioides difficile sporulation – Pola Kuhn – PLOS Genetics

Microbial Genomics & Systems Biology

A systems biology approach to find representative genes in Acute Myeloid Leukemia– Behnam Aghajan – PLOS ONE

Aquatic & Animal Microbiology

Influence of salinity on growth, nutrient utilization, and gene expression of giant freshwater prawn (Macrobrachium rosenbergii) – Farhana Ahamed Shanila – PLOS ONE

Metabolism, Inflammation & Human Health

Integrated computational analysis identifies FABP4, PTGS2, and HPGD as key molecular targets linking PET microplastic exposure to metabolic dysfunction-associated steatotic liver disease – Yi Zhang – PLOS ONE

Exploring the mechanism of Shuangyu Granule in regulating immune-inflammatory responses in influenza through UPLC-Orbitrap-MS/MS, GC-MS, and network target analysis – Ling Sun – PLOS ONE

Cardiometabolic risk pathways in adults with disabilities: A structural equation model of diet quality and functional ability – Radwan Qasrawi – PLOS ONE

Neuroscience & Neurodegeneration

Research advances in key genes and regulatory mechanisms of posttranslational modifications in Parkinson’s disease – Bangzhi Wang – PLOS ONE

Clinical & Healthcare Research

HF-OCAQ: Oral comfort assessment in heart failure patients – Mei Lu – PLOS ONE

Mental Health

Spirituality as a coping resource: Towards integration into mental health framework – Sajama Nepali – PLOS Mental Health

December 19, 2025

Animal microbiome

The innate immune IMD pathway is a key regulator of gut microbiome and metabolic homeostasis in the black tiger shrimp (Penaeus monodon) – Premruethai Supungul – PLOS ONE


Human gut microbiome & nutrition

The evaluation of indoxyl sulfate in the general population in Kanegasaki Iwate: A cross-sectional study (KANEGASAKI study) – Mizuki Hisano – PLOS ONE

The relationship between dietary intake of B vitamins and Helicobacter pylori seropositivity – Yuexia Lu – PLOS ONE


Plant, soil & ecological microbiome

Zinc ion increases the effectiveness of phosphorus in agricultural soils through microbial solubilization – Lanxin Tang – PLOS ONE

Optimizing soil quality and rhizosphere ecology to enhance Annona squamosa yield and quality through water–fertilizer–mulching synergy – Weihua Wang – PLOS ONE

Concentration-dependent effects of fermented spent coffee grounds and contrasting effects of earthworms on growth and phytochemicals in medicinal plant Glechoma longituba – Bing-Nan Zhao – PLOS ONE


Animal experiments (model organisms)

The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient limitation – Daniela Barraza – PLOS Genetics

High-protein diets reduce plasma pro-inflammatory cytokines following lipopolysaccharide challenge in Swiss Albino mice – Hellen W Kinyi – PLOS ONE


Clinical research & public health

Impact of an integrated intervention package during preconception, pregnancy, and early childhood on inflammation, IGF-1, IGFBP3 during first 6 months of life: Findings from the WINGS randomized controlled trial – Ranadip Chowdhury – PLOS Global Public Health

Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ≥50 years – Jose-Ramon Blanco – PLOS ONE

Effect of obesity and exercise training on circulating lipids in American Indian adolescents – Charles F Hojjat – PLOS ONE

From mental health detention to health systems reform: Co-producing policy and practice recommendations with Black men and their communities – Elaine Craig – PLOS Mental Health


Microbial genetics & bacterial physiology

Whole-genome analysis of Lysinibacillus boronitolerans MSR1: A dairy-isolated multidrug-resistant and non-pathogenic strain – Md Shahedur Rahman – PLOS ONE

A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and intra-species cooperation – Ben Vezina – PLOS Biology


Clinical biomarkers & immunology

Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis – John E Lafleur – PLOS ONE

Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis – Lei Guo – PLOS ONE


Oral health & microbiome

The impact of diet and oral hygiene on dental caries among Turkish children: A cross-sectional study – Ozge Yesildemir – PLOS ONE


Molecular biology & immunity

LIPL-1 and LIPL-2 are TCER-1-regulated lysosomal lipases with distinct roles in immunity and fertility – Laura Bahr – PLOS Genetics