The highlighted paper of the day looked at the relationship between statins and gut microbiome / enterotype prevalence, mined from data collected from the MetaCardis study which looked at over 2000 participants all across the EU and collected over 1,400 parameters.
If you’re looking for a review/news article of the paper head to: Statin drugs might boost healthy gut microbes
If you’re looking for the paper: Statin therapy is associated with lower prevalence of gut microbiota dysbiosis – Sara Silva – Nature
COVID-19
Identification of Drugs Blocking SARS-CoV-2 Infection using Human Pluripotent Stem Cell-derived Colonic Organoids – Xiaohua Duan – bioRxiv
Whose coronavirus strategy worked best? Scientists hunt most effective policies – Elizabeth Gibney – Nature
Coronavirus activates a stem cell-mediated defense mechanism that accelerates the activation of dormant tuberculosis: implications for the COVID-19 pandemic – Lekhika Pathak – bioRxiv
General Microbiome
Multi ‘Omics Profiling of the HIV Airway Epithelium: Integration of the Microbiome, Methylome, and Transcriptome – MS Jude – Am J Respir Crit Care Med
Intracellular Staphylococcus aureus persisters upon antibiotic exposure – Frederuc Peyrusson – Nature Communications
MiniReview: A toxic environment: a growing understanding of how microbial communities affect Shiga toxin expression by E. coli O157:H7 – Erin M. Nawrocki – American Society for Microbiology, Applied and Environmental Microbiology
Pregnancy and early life
Gut microbiota derived metabolites contribute to intestinal barrier maturation at the suckling-to- weaning transition – Martin Beaumont – Gut Microbes
Gut Microbiome Derived 12,13 Dihome Promotes Antigen Presenting Cell Dysfunction In Vitro and Airway Allergic Inflammation In Vivo – S Levan – Atsjournal
Multi-site human microbiome
The Microbiome and the Gut‐Liver‐Brain Axis for CNS Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models – Kyle Hawkins – Clinical Pharmacology and Therapeutics
Gut Check: The Intestinal Microbiome Does Not Predict or Protect from Vancomycin- Resistant Enterococcus Acquisition Among Critically Ill Patients – Chanderraj – Atsjournal
The Tumour-Resident Microbiome Is Associated with Cancer Hypomethylation Status in Lung Adenocarcinoma – Marshall – atsjournal
An association between the gut microbiota and immune cell dynamics in humans. – Jonas Schluter – bioRxiv
Metabolomics
Analyzing the impact of Mycobacterium tuberculosis infection on primary human macrophages by combined exploratory and targeted metabolomics – Vrieling Frank
Review: Metabolome–Microbiome Crosstalk and Human Disease – Kathleen Lee-Sarwar – metabolites
Animal Microbiome
Review – Mycobacterium bovis: From Genotyping to Genome Sequencing – Ana Guimaraeas – Microorganism
Animal experiments
Staphylococcus aureus-induced proteomic changes in the mammary tissue of rats: A TMT-based study – Lirong Cai – Plos One
Plant, root, and soil microbiome
Effects of earthworms on the microbiomes and antibiotic resistomes of detritus fauna and phyllosphere – Dong Zhu – Environmental Science and Technology
Surface runoff alters cave microbial community structure and function – Madison Davis – Plos One
Water and extremophile microbiome
Culturing of ‘Unculturable’ Subsurface Microbes: Natural Organic Carbon Source Fuels the Growth of Diverse and Distinct Bacteria from Groundwater – Xiaoqin Wu – bioRxiv
Bioinformatics & Techniques
Sequence count data are poorly fit by the negative binomial distribution – Stjin Hawinkel – Plos One
Book Chappter: Meta-Pangenome: At the Crossroad of Pangenomics and Metagenomics – Bing MA – The Pangenome, Springer.
Snipe: Highly sensitive pathogen detection from metagenomic sequencing data – Lihong Huang – bioRxiv
Validated Method for the Study of Human Lung Microbiota from Excised Tissue – Dumont-Leblond – atsjounal
Microbes in the news
Bad to the Bone – Matthew Greseth- MUSC Health
Meet the ‘psychobiome’: the gut bacteria that may alter how you think, feel, and act – Elizabeth Pennisi – ScienceMag
Decoding the Microbiome: Essential to Advancing Precision Medicine – Heather Hall – rdworldonline
Harithaa’s non-microbiology picks!
Mass spectrometry for future atomic clocks – Marianna Safrova – Nature (news & views)
