Tag Archives: Mouse model

December 19, 2025

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Animal microbiome

The innate immune IMD pathway is a key regulator of gut microbiome and metabolic homeostasis in the black tiger shrimp (Penaeus monodon) – Premruethai Supungul – PLOS ONE

Human gut microbiome & nutrition

The evaluation of indoxyl sulfate in the general population in Kanegasaki Iwate: A cross-sectional study (KANEGASAKI study) – Mizuki Hisano – PLOS ONE

The relationship between dietary intake of B vitamins and Helicobacter pylori seropositivity – Yuexia Lu – PLOS ONE

Plant, soil & ecological microbiome

Zinc ion increases the effectiveness of phosphorus in agricultural soils through microbial solubilization – Lanxin Tang – PLOS ONE

Optimizing soil quality and rhizosphere ecology to enhance Annona squamosa yield and quality through water–fertilizer–mulching synergy – Weihua Wang – PLOS ONE

Concentration-dependent effects of fermented spent coffee grounds and contrasting effects of earthworms on growth and phytochemicals in medicinal plant Glechoma longituba – Bing-Nan Zhao – PLOS ONE

Animal experiments (model organisms)

The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient limitation – Daniela Barraza – PLOS Genetics

High-protein diets reduce plasma pro-inflammatory cytokines following lipopolysaccharide challenge in Swiss Albino mice – Hellen W Kinyi – PLOS ONE

Clinical research & public health

Impact of an integrated intervention package during preconception, pregnancy, and early childhood on inflammation, IGF-1, IGFBP3 during first 6 months of life: Findings from the WINGS randomized controlled trial – Ranadip Chowdhury – PLOS Global Public Health

Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ≥50 years – Jose-Ramon Blanco – PLOS ONE

Effect of obesity and exercise training on circulating lipids in American Indian adolescents – Charles F Hojjat – PLOS ONE

From mental health detention to health systems reform: Co-producing policy and practice recommendations with Black men and their communities – Elaine Craig – PLOS Mental Health

Microbial genetics & bacterial physiology

Whole-genome analysis of Lysinibacillus boronitolerans MSR1: A dairy-isolated multidrug-resistant and non-pathogenic strain – Md Shahedur Rahman – PLOS ONE

A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and intra-species cooperation – Ben Vezina – PLOS Biology

Clinical biomarkers & immunology

Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis – John E Lafleur – PLOS ONE

Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis – Lei Guo – PLOS ONE

Oral health & microbiome

The impact of diet and oral hygiene on dental caries among Turkish children: A cross-sectional study – Ozge Yesildemir – PLOS ONE

Molecular biology & immunity

LIPL-1 and LIPL-2 are TCER-1-regulated lysosomal lipases with distinct roles in immunity and fertility – Laura Bahr – PLOS Genetics

December 12, 2025

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Animal microbiome

Human-derived fecal virome transplantation (FVT) reshapes the murine gut microbiota and virome, enhancing glucose regulation – Cervantes-Echeverría – PLOS ONE

TTSS-2 virulence drives inflammatory destruction of the gut epithelial barrier and modulates inflammatory response profiles in the Salmonella-infected mouse gut – Enz – PLOS Pathogens

Aspartic protease 2 from Trichinella spiralis excretion/secretion products hydrolyzes tight junctions of intestinal epithelial cells – Long – PLOS NTDs

Endosymbiont hijacking of acylcarnitines regulates insect vector fecundity by suppressing the viability of stored sperm – Weiss – PLOS Genetics

Development and validation of a quantitative real-time PCR assay for enumeration of Clostridium sporogenes in meat products – Schuller – PLOS ONE

Rooting for data: A FAIR research data management environment for Plant-Microbe collaboration – Dröst – PLOS Pathogens (Plant microbiome)

Prolonged starvation deepens quiescence in Vasa2/Piwi1-expressing cells of a sea anemone – Pascual-Carreras – PLOS Biology

Host–microbe interactions / Immunology

Gut bacteria induce heterologous immune priming in Rhodnius prolixus encompassing humoral and cellular responses – Gilliland – PLOS Pathogens

Dietary flavonoids may improve insulin resistance: NHANES + in vitro – Sui – PLOS ONE

Antiviral and immune-modulatory activities of STING agonists in persistent HBV infection – Wang – PLOS Pathogens

Endosymbiont metabolic manipulation affecting insect reproduction – Weiss – PLOS Genetics

Human clinical studies / Metabolism

Effects of risperidone on amino acid metabolism, glucose & kidney function – Oshima – PLOS ONE

Association between Anti-H. pylori IgG and coronary heart disease – Wang – PLOS ONE

Benefits of psychosocial support for adolescent mothers in Uganda – Nakyaze – PLOS ONE

Modifiable risk factors for inflammatory bowel disease in Kuwait – Alhasan – PLOS ONE

Exposure to polystyrene nanoparticles disrupts trophoblast mitochondrial homeostasis – Hao – PLOS ONE

Molecular mechanisms of lipid metabolism abnormalities driving sepsis & atrial fibrillation – Ou – PLOS ONE

Multi-dimensional analysis of global colorectal cancer burden (1990–2021) – Sun – PLOS ONE

Computational / Modeling

Identification of dynamic models of microbial communities – Paredes-Vázquez – PLOS Comp Biol

Accuracy limits of the Lotka–Volterra model in strongly coupled microbial systems – Mustri – PLOS Comp Biol

Plant, soil & ecological microbiome

High-resolution melting assays for discrimination of fungal pathogens in grapevine trunk disease – Azevedo-Nogueira – PLOS ONE

Rooting for data: FAIR data environment for plant–microbe collaboration – Dröst – PLOS Pathogens

Environmental health / Climate / Water

Bridging water, health and climate: A call to action – Hedke – PLOS Water