Have a good Friday! Today was published a very interesting article about a longitudinal study using several tools (including microbiome analysis), finding several clinically actionable health discoveries and identified multiple molecular pathways associated with metabolic, cardiovascular and oncologic pathophysiology, in patients with type II diabetes. This article could represent an interesting contribution to precision medicine development.

In addition, this digest also contains papers about: the role of sphingolipids in symbiosis and gut health, the role of fecal microbiota transplantation in IBS relief, the stability of a probiotic strain in infants, and more…

 

Human/General Microbiome

A longitudinal big data approach for precision health – Sophia Miryam Schüssler-Fiorenza Rose – Nature Medicine

Turning points: Making the microbiome personal – Ami S. Bhatt – Nature Medicine

Bacteroides-Derived Sphingolipids Are Critical for Maintaining Intestinal Homeostasis and Symbiosis – Eric M. Brown – Cell Host & Microbe

Relief of irritable bowel syndrome by fecal microbiota transplantation is associated with changes in diversity and composition of the gut microbiota – Hong Li Huang – Journal of Digestive Diseases

Perspective: Do Interactions Between Environmental Chemicals and the Human Microbiome Need to Be Considered in Risk Assessments? – Joseph Rodricks – Risk Analysis

Association of the oral microbiome with the progression of impaired fasting glucose in a Chinese elderly population – Rui-Rui Wang – Journal of Oral Microbiology

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke – Geng-Hong Xia – Frontiers in Neurology

Review: Alpha-Synuclein Pathology and the Role of the Microbiota in Parkinson’s Disease – Emily Fitzgerald – Frontiers in Neuroscience

Mucosal-associated invariant T cells and oral microbiome in persistent apical periodontitis – Haleh Davanian – International Journal of Oral Science

Obesity, Xenobiotic Intake and Antimicrobial-Resistance Genes in the Human Gastrointestinal Tract: A Comparative Study of Eutrophic, Overweight and Obese Individuals – Marjorie Raquel Anariba Sarmiento – Genes

Effects of Intestinal Microbial⁻Elaborated Butyrate on Oncogenic Signaling Pathways – Jiezhong Chen – Nutrients

Composite Analysis of the Virome and Bacteriome of HIV/HPV Co-Infected Women Reveals Proxies for Immunodeficiency – Juliana D. Siqueira – Viruses

 

Animal Microbiome and Animal Model Experiments

Review: Veterinary ocular microbiome: Lessons learned beyond the culture – Kayla C. Banks – Veterinary Ophthalmology  

Antibiotic-Induced Disruption of Gut Microbiota Alters Local Metabolomes and Immune Responses – Lin Sun – Frontiers in Cellular and Infection Microbiology

Cloacal microbiomes and ecology of individual barn swallows – Roberto Ambrosini – FEMS Microbiology Ecology

Exposure to microplastics lowers arsenic accumulation and alters gut bacterial communities of earthworm Metaphire californica – Hong-Tao Wang – Environmental Pollution

Fermented carrot juice attenuates type 2 diabetes by mediating gut microbiota in rats – Rongkang Hu – Food and Function

Positive effects of a Clostridium butyricum-based compound probiotic on growth performance, immune responses, intestinal morphology, hypothalamic neurotransmitters, and colonic microbiota in weaned piglets – Guangtian Cao – Food and Function

Ripened Pu-erh tea extract protects mice from obesity by modulating gut microbiota composition – Xiaojie Lu – Journal of Agricultural and Food Chemistry

Microbiota alter metabolism and mediate neurodevelopmental toxicity of 17β-estradiol – Tara R. Catron – Scientific Reports

 

Beneficial Microbes and Compounds

Vitamin C and B3 as New Biomaterials to Alter Intestinal Stem Cells – Yijun Qi – Journal of Biomedical Material Research

Bile salt hydrolase can improve Lactobacillus plantarum survival in gastrointestinal tract by enhancing their adhesion ability – Yanrong Liu – FEMS Microbiology Letters

Administration of the Probiotic Escherichia coli Strain A0 34/86 Resulted in a Stable Colonization of the Human Intestine During the First Year of Life – Lenka Micenková – Probiotics and Antimicrobial Proteins

Minireview: Structures and Metabolic Properties of Bovine Milk Oligosaccharides and Their Potential in the Development of Novel Therapeutics – Randall C. Robinson – Frontiers in Nutrition

 

Bioinformatics and Analysis

An Adaptive Multivariate Two-Sample Test With Application to Microbiome Differential Abundance Analysis – Kalins Banerjee – Frontiers in Genetics

Identifying Gut Microbiota Associated With Colorectal Cancer Using a Zero-Inflated Lognormal Model – Dongmei Ai – Frontiers in Microbiology