Tag Archives: clinical trial

January 23, 2026

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Animal microbiome

Bacterial-archaeal co-occurrence in honey bee gut microbiomes across host species and management regimes -Jian-Ping Ying –PLOS ONE

Bacterial community associated with the surface and inside of centipede forcipules: Identification and characterization -Yasutaka Tanaka – PLOS ONE

Human reproductive & urinary microbiome

Vaginal chlorhexidine gluconate versus fluconazole for recurrent vulvovaginal candidiasis: A randomized noninferiority trial – Cathrin Alvendal – PLOS ONE

Infection and transplantation / Host–microbe interactions

DnaK supports intracellular persistence of Staphylococcus xylosus and confers mechanical resilience to a human breast cancer cell line – Lei Ye – PLOS ONE

Investigation of a viable but non-culturable state in Porphyromonas gingivalis and host cell invasion – Adenrele Oludiran – PLOS ONE

Microbial ecology & symbiosis

Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis – Sunnyjoy Dupuis – PLOS ONE

Oral microbiome & animal experiments

Effects of glycyrrhizin on healing and prevention of recurrent aphthous stomatitis in hamster models – Fumie Shiba – PLOS ONE

Plant, soil & ecological microbiome

Tree species-specific strategies of soil aggregation driven by SOC–GRSP coupling under nitrogen addition and precipitation reduction -Mingxin Zhou – PLOS ONE

Microbial genomics & bioremediation

Genomic analysis of Acinetobacter baumannii DUEMBL6 reveals diesel bioremediation potential and biosafety concerns – Nizam Uddin – PLOS ONE

Human gut & inflammatory disease

Identification of hypoxia- and mitophagy-related diagnostic biomarkers for ulcerative colitis based on bioinformatic analysis and machine learning – Zewei Sheng – PLOS ONE

Oral & dental archaeology / Ancient microbiome

Paleo-proteomic analysis of Iron Age dental calculus provides direct evidence of Scythian reliance on ruminant dairy – Jaruschka Pecnik – PLOS ONE

Cancer & clinical oncology

Radiomics profiling combined with clinical risk factors for preoperative lymphatic metastasis prediction in colorectal cancer: A multicenter study – Fangda Guo – PLOS ONE

Toxicology & respiratory health

Potential mechanisms and effects of AFB1-induced asthma: A comprehensive analysis based on network toxicology and molecular docking – Zhiyue Yu – PLOS ONE

Human development & diet (archaeology / isotopes)

Fed the same way? Exploring the influence of breastfeeding, weaning, and childhood diet on adult sex ratios through stable isotope analysis of incremental dentine in Medieval Tuscany – Alessio Amaro – PLOS ONE

December 19, 2025

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Animal microbiome

The innate immune IMD pathway is a key regulator of gut microbiome and metabolic homeostasis in the black tiger shrimp (Penaeus monodon) – Premruethai Supungul – PLOS ONE

Human gut microbiome & nutrition

The evaluation of indoxyl sulfate in the general population in Kanegasaki Iwate: A cross-sectional study (KANEGASAKI study) – Mizuki Hisano – PLOS ONE

The relationship between dietary intake of B vitamins and Helicobacter pylori seropositivity – Yuexia Lu – PLOS ONE

Plant, soil & ecological microbiome

Zinc ion increases the effectiveness of phosphorus in agricultural soils through microbial solubilization – Lanxin Tang – PLOS ONE

Optimizing soil quality and rhizosphere ecology to enhance Annona squamosa yield and quality through water–fertilizer–mulching synergy – Weihua Wang – PLOS ONE

Concentration-dependent effects of fermented spent coffee grounds and contrasting effects of earthworms on growth and phytochemicals in medicinal plant Glechoma longituba – Bing-Nan Zhao – PLOS ONE

Animal experiments (model organisms)

The Drosophila G protein-coupled receptor, GulpR, is essential for lipid mobilization in response to nutrient limitation – Daniela Barraza – PLOS Genetics

High-protein diets reduce plasma pro-inflammatory cytokines following lipopolysaccharide challenge in Swiss Albino mice – Hellen W Kinyi – PLOS ONE

Clinical research & public health

Impact of an integrated intervention package during preconception, pregnancy, and early childhood on inflammation, IGF-1, IGFBP3 during first 6 months of life: Findings from the WINGS randomized controlled trial – Ranadip Chowdhury – PLOS Global Public Health

Lack of association between loneliness, social isolation and inflammation in people living with HIV aged ≥50 years – Jose-Ramon Blanco – PLOS ONE

Effect of obesity and exercise training on circulating lipids in American Indian adolescents – Charles F Hojjat – PLOS ONE

From mental health detention to health systems reform: Co-producing policy and practice recommendations with Black men and their communities – Elaine Craig – PLOS Mental Health

Microbial genetics & bacterial physiology

Whole-genome analysis of Lysinibacillus boronitolerans MSR1: A dairy-isolated multidrug-resistant and non-pathogenic strain – Md Shahedur Rahman – PLOS ONE

A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism and intra-species cooperation – Ben Vezina – PLOS Biology

Clinical biomarkers & immunology

Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis – John E Lafleur – PLOS ONE

Multi-omics analysis reveals diagnostic and therapeutic biomarkers for aging phenotypes in ulcerative colitis – Lei Guo – PLOS ONE

Oral health & microbiome

The impact of diet and oral hygiene on dental caries among Turkish children: A cross-sectional study – Ozge Yesildemir – PLOS ONE

Molecular biology & immunity

LIPL-1 and LIPL-2 are TCER-1-regulated lysosomal lipases with distinct roles in immunity and fertility – Laura Bahr – PLOS Genetics