February 21, 2020

This Friday, read about the potential influence of microbiomes in hominin evolution, gut microbiome in patients with Sjögren’s syndrome, new antibiotics discovered through comparative genomics, and more. Happy reading!

General microbiome

*The Internal, External and Extended Microbiomes of Hominins – Robert R. Dunn – Front. Ecol. Evol.

A Deep Learning Approach to Antibiotic Discovery– Jonathan M. Stokes – Cell

Review: Next-generation physiology approaches to study microbiome function at single cell level – Roland Hatzenpichler – Nature Reviews Microbiology

Patterns of partnership: surveillance and mimicry in host-microbiota mutualisms – Travis J Wiles & Karen Guillemin – Current Opinion in Microbiology

Review: Innovative and rapid antimicrobial susceptibility testing systems – Alex van Belkum – Nature Reviews Microbiology

Gut microbiome

*Gut dysbiosis is prevailing in Sjögren’s syndrome and is related to dry eye severity– Jayoon Moon – PlosOne

Review: Healthy Human Gastrointestinal Microbiome: Composition and Function After a Decade of Exploration – Wenly Ruan – Digestive Diseases and Sciences

Review: Gut microbiota-derived metabolites as key actors in inflammatory bowel disease– Aonghus Lavelle & Harry Sokol – Nature Reviews Gastroenterology & Hepatology

Review: Microbiome in Colorectal Cancer: How to Get from Meta-omics to Mechanism?–Dominik Ternes – Trends in Microbiology

Urinary microbiome

Review: Urinary tract infections: microbial pathogenesis, host–pathogen interactions and new treatment strategies – Roger D. Klein & Scott J. Hultgren – Nature Reviews Microbiology

Vaginal microbiome

The microbiome and gynaecological cancer development, prevention and therapy – Paweł Łaniewski – Nature Reviews Urology

Animal microbiome

Coordinated transformation of the gut microbiome and lipidome of bowhead whales provides novel insights into digestion – Carolyn A. Miller – The ISME Journal

Animal experiment

*Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling – Elizabeth J. Culp – Nature

The Gene Expression Profile of Uropathogenic Escherichia coli in Women with Uncomplicated Urinary Tract Infections Is Recapitulated in the Mouse Model – Arwen E. Frick-Cheng – bioRxiv

Sustained IFN-I stimulation impairs MAIT cell responses to bacteria by inducing IL-10 during chronic HIV-1 infection – X. Tang – Science Advance

Bioinformatics

Microbial resolution of whole genome shotgun and 16S amplicon metagenomic sequencing using publicly available NEON data– Kyle D. Brumfield – PlosOne

Viruses & Phages

Respiratory viruses in mechanically ventilated patients: a pilot study – Raquel Nazareth – BMC Pulmonary Medicine

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