August 20, 2022

Have a nice weekend! Today, in this brief Digest: Lung microbiota and PM exposure, Akkermansia genomic variability, sulfonation, microbiome and cholesterol, and a new role for Blautia wexlerae.

Human and General Microbiome

The Lung Microbiota Affects Pulmonary Inflammation and Oxidative Stress Induced by PM(2.5) Exposure – Simin Wang – Environmental Science & Technology

A thousand metagenome-assembled genomes of Akkermansia reveal phylogroups and geographical and functional variations in the human gut – Qing-Bo Lv – Frontiers in Cellular and Infection Microbiology

Intestinal TLR4 deletion exacerbates acute pancreatitis through gut microbiota dysbiosis and Paneth cells deficiency – Mei Qi-Xiang – Gut Microbes

A biosynthetic pathway for the selective sulfonation of steroidal metabolites by human gut bacteria – Lina Yao – Nature Microbiology

Review: Altered gut microbiota patterns in COVID-19: Markers for inflammation and disease severity – Chiranjib Chakraborty – World Journal of Gastroenterology

Animal Model Microbiome and Experiments

Characterization of interactions of dietary cholesterol with the murine and human gut microbiome – Henry H Le – Nature Microbiology

Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction – Torsten P M Scheithauer – Gut Microbes

Rapid evolution of a novel protective symbiont into keystone taxon in Caenorhabditis elegans microbiota – Alejandra Wu-Chuang – Scientific Reports

Beneficial Microbes and Compounds

Oral administration of Blautia wexlerae ameliorates obesity and type 2 diabetes via metabolic remodeling of the gut microbiota – Koji Hosomi – Nature Communications

Fecal microbiota transplantation can improve cognition in patients with cognitive decline and Clostridioides difficile infection – Soo-Hyun Park – Aging

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