Highlights!

Extending and improving metagenomic taxonomic profiling with uncharacterized species using MetaPhlAn 4 – Aitor Blanco-Míguez – Nature Biotechnology

Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease – Raaj S Mehta – Nature Medicine

Human and General Microbiome

Interpersonal variability of the human gut virome confounds disease signal detection in IBD – Stephen R Stockdale – Communications Biology

Clinical characteristics, diagnosis, outcomes and lung microbiome analysis of invasive pulmonary aspergillosis in the community-acquired pneumonia patients – Zhi Ao – BMJ Open Respiratory Research

Comparing the gut microbiome of obese, African American, older adults with and without mild cognitive impairment – Andrew McLeod – PloS One

Beneficial Microbes and Compounds

Capacity of a Microbial Synbiotic To Rescue the In Vitro Metabolic Activity of the Gut Microbiome following Perturbation with Alcohol or Antibiotics – Braden T Tierney – Applied and Environmental Microbiology

Animal Microbiome

A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging – Robert Sonowal – Science Advances

A longitudinal survey in the wild reveals major shifts in fish host microbiota after parasite infection – Eglantine Mathieu-Bégné – Molecular Ecology

Matrine alleviates depressive-like behaviors via modulating microbiota-gut-brain axis in CUMS-induced mice – Ming Zhang – Journal of Translational Medicine

Variations in gut microbiome and metabolites of dogs with acute diarrhea in poodles and Labrador retrievers – Huasong Bai – Archives of Microbiology

Environmental Microbiome

Enzyme adaptation to habitat thermal legacy shapes the thermal plasticity of marine microbiomes – Ramona Marasco – Nature Communications

Microbiome Analysis: Tools and Techniques

Review: Computational methods and challenges in analyzing intratumoral microbiome data – Qi Wang – Trends in Microbiology

Robust Bioinformatics Approaches Result in the First Polygenic Risk Score for BMI in Greek Adults – Maria Kafyra – Journal of Personalized Medicine

Development of a tongue image-based machine learning tool for the diagnosis of gastric cancer: a prospective multicentre clinical cohort study – Li Yuan – EClinicalMedicine

Latent dirichlet allocation for double clustering (LDA-DC): discovering patients phenotypes and cell populations within a single Bayesian framework – Elie-Julien El Hachem – BMC Bioinformatics