Today’s digest contains several great recent papers, but in particular I’d like to highlight a Nature Methods paper on applying network biology approaches to the microbiome, and a Nature paper which disentangles the effects of drugs and disease on host and microbiome.
Fast and flexible analysis of linked microbiome data with mako – Röttjers & Faust – Nature Methods.
Combinatorial, additive and dose-dependent drug–microbiome associations – Forslund et al. Nature
Mammalian gut metabolomes mirror microbiome composition and host phylogeny – Gregor et al. – ISME
Human gut microbiome
Microbial co-occurrence complicates associations of gut microbiome with US immigration, dietary intake and obesity – Wang et al. – Genome Biology
Signature changes in gut microbiome are associated with increased susceptibility to HIV-1 infection in MSM – Chen et al. – Microbiome
Cognitive behavioral therapy for irritable bowel syndrome induces bidirectional alterations in the brain-gut-microbiome axis associated with gastrointestinal symptom improvement – Jacobs et al. – Microbiome.
Human oral microbiome
Impact of sleep on the microbiome of oral biofilms – Sotozono et al. – PLOS One
The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota – Blake et al. – Cell Reports Medicine
Sexual dimorphism in glucose metabolism is shaped by androgen-driven gut microbiome – Gao et al. – Nature Communications