Have a nice Friday! Today, in this Digest, a study published in Nature showing exciting associations between the microbiome and the human serum metabolome; we also have different papers about different respiratory system health conditions, different paediatric studies, and studies on the microbiome in different genitourinary health conditions. It is worth to highlight as well another study (Ford et al., Molecular Biology and Evolution) about how in vivo microbiome coevolution can influence host immunity.

Human and General Microbiome

Review: The gut microbiome as a target for adjuvant therapy in obstructive sleep apnea – Mohammad Badran – Expert Opinion on Therapeutic Targets

Review: The microbiome, genetics, and gastrointestinal neoplasms: the evolving field of molecular pathological epidemiology to analyze the tumor-immune-microbiome interaction – Kosuke Mima – Human Genetics 

Review: Faecal microbiota transplantation: what’s beyond Clostridium difficile infection? – Aravind Gokula Tamilarasan – European Journal of Gastroenterology & Hepatology 

Review: A bridge for short-chain fatty acids to affect inflammatory bowel disease, type 1 diabetes, and non-alcoholic fatty liver disease positively: by changing gut barrier – Wangxin Liu – European Journal of Nutrition

A reference map of potential determinants for the human serum metabolome – Noam Bar – Nature

Commentary: Building a chemical blueprint for human blood – Patrick H. Bradley & Katherine S. Pollard

In vivo microbial coevolution favours host protection and plastic downregulation of immunity – Suzanne A Ford – Molecular Biology and Evolution

Mucin-Degrading Microbes Release Monosaccharides That Chemoattract Clostridioides difficile and Facilitate Colonization of the Human Intestinal Mucus Layer – Melinda A. Engevik – ACS Infectious Diseases

The gut microbiome drives inter- and intra-individual differences in metabolism of bioactive small molecules – Asimina Kerimi – Scientific Reports

Gut Microbiota Changes and Their Relationship with Inflammation in Patients with Acute and Chronic Insomnia –  Li Y – Dovepress 

Microbiome and Respiratory System Health

Lower airway dysbiosis affects lung cancer progression – Jun-Chieh J Tsay – Cancer Discovery

Variations in fecal microbial profiles of acute exacerbation and stable-state chronic obstructive pulmonary disease – Yonghong Wu – Life Sciences

Correlation between adenotonsillar microbiome and clinical characteristics of pediatrics with snoring – Kyung Soo Kim – Clinical and Experimental Otorhinolaryngology 

Microbiome and Paediatrics

Delivery mode and gut microbial changes correlate with an increased risk of childhood asthma – Jakob Stokholm – Science Translational Medicine

Intestinal Microbiota in Children With Symptomatic Dientamoeba fragilis Infection: A Case-control Study – Michael W. van Kalleveen – The Pediatric Infectious Disease Journal

Genito-urinary Tract Microbiome

Influence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls – Christina Farr Zuend – AIDS

Bare Versus Hair: Do Pubic Hair Grooming Preferences Dictate the Urogenital Microbiome? – Julia Geynisman-Tan – Female Pelvic Medicine & Reconstructive Surgery

Beneficial Microbes and Compounds

A polysaccharide from Fagopyrum esculentum Moench bee pollen alleviates microbiota dysbiosis to improve intestinal barrier function in antibiotic-treated mice – Liuying Zhu – Food and Function

Phytogenic products, used as alternatives to antibiotic growth promoters, modify the intestinal microbiota derived from a range of production systems: an in vitro model – Yadav S. Bajagai – Applied Microbiology and Biotechnology

COVID-19 and Microbiota

COVID-19 in the Developing World: Is the Immune Response to α-Gal an Overlooked Factor Mitigating the Severity of Infection? – Adnan Hodžić – ACS Infectious Diseases

Animal Microbiome / Animal Models

Effects of Vitamin D3 on Intestinal Flora in a Mouse Model of Inflammatory Bowel Disease Treated with Rifaximin – Zijun Gu – Medical Science Monitor

Gut microbiota depletion by chronic antibiotic treatment alters the sleep/wake architecture and sleep EEG power spectra in mice – Yukino Ogawa – Scientific Reports

Comparison of different modes of antibiotic delivery on gut microbiota depletion efficiency and body composition in mouse – Pauline Tirelle – BMC Microbiology

Plant Microbiome

Plant resistome profiling in evolutionary old bog vegetation provides new clues to understand emergence of multi-resistance – Melanie Maria Obermeier – The ISME Journal

Other

A network-based approach to deciphering a dynamic microbiome’s response to a subtle perturbation – Grace Tzun-Wen Shaw – Scientific Reports

A comprehensive investigation of metagenome assembly by linked-read sequencing – Lu Zhang – Microbiome (BMC)

Light-Activated Electron Transfer and Catalytic Mechanism of Carnitine Oxidation by Rieske-type Oxygenase from Human Microbiota – Muralidharan Shanmugam – Angewandte Chemie

Microbial communities and gene contributions in smokeless tobacco products – A. J. Rivera – Applied Microbiology and Biotechnology