Greetings from Chile! Today, in this Digest, it is worth to highlight: a study showing associations between the use of antibiotics and the risk of appendicitis, a review about microbiota and colorectal cancer (CRC) risk and another review about markers for diabetes-associated chronic kidney disease. In addition, there are a set of papers about microbiome changes under short- and long-term antibiotic use in the animal lab, and microbiota changes in the treatment of non-model animals, such as the sika deer.   

Human Microbiome

Antibiotics during childhood and development of appendicitis-a nationwide cohort study – Jacob Antonsen – Alimentary Pharmacology and Therapeutics

Review: Bacteria-related changes in host DNA methylation and the risk for CRC – Iradj Sobhani – Gut Microbes

Review: Potential for Novel Biomarkers in Diabetes-Associated Chronic Kidney Disease: Epigenome, Metabolome, and Gut Microbiome – Ashani Lecamwasam – Biomedicines

Microbiota-Mitochondria Inter-Talk: A Potential Therapeutic Strategy in Obesity and Type 2 Diabetes – Teresa Vezza – Antioxidants

Preprint: Impact of sleep fragmentation, heart failure, and their combination, on the gut microbiome – Olfat Khannous-Lleiffe – BioRxiv

Microbiome and Diet

Relative abundance of the Prevotella genus within the human gut microbiota of elderly volunteers determines the inter-individual responses to dietary supplementation with wheat bran arabinoxylan-oligosaccharides – Wing Sun Faith Chung – BMC Microbiology

Animal Microbiome

Acute and long-term effects of antibiotics commonly used in laboratory animal medicine on the fecal microbiota – Scott W. Korte – Veterinary Research

The impact of anthelmintic treatment on gut bacterial and fungal communities in diagnosed parasite-free sika deer Cervus nippon – Xiaolong Hu – Applied genetics and molecular biotechnology

On the way to specificity – Microbiome reflects sponge genetic cluster primarily in highly structured populations – Cristina Díez‐Vives – Molecular Ecology

The gut microbiota may be a novel pathogenic mechanism in loosening of orthopedic implants in rats – Meghan M. Moran – The FASEB Journal

Characterization of Gut Microbiota in Prenatal Cold Stress Offspring Rats by 16S rRNA Sequencing – Jiasan Zheng – Animals

Obesity Worsens Gulf War Illness Symptom Persistence Pathology by Linking Altered Gut Microbiome Species to Long-Term Gastrointestinal, Hepatic, and Neuronal Inflammation in a Mouse Model – Dipro Bose – Nutrients

Beneficial Microbes and Compounds

Influence of a cholesterol-lowering strain Lactobacillus plantarum LP3 isolated from traditional fermented yak milk on gut bacterial microbiota and metabolome of rats fed with a high-fat diet – Zitong Ding – Food and Function

The Microbiota-Derived Metabolite of Quercetin, 3,4-Dihydroxyphenylacetic Acid Prevents Malignant Transformation and Mitochondrial Dysfunction Induced by Hemin in Colon Cancer and Normal Colon Epithelia Cell Lines – Mabel Catalán – Molecules

Bioinformatics

Constructing bi-plots for random forest: Tutorial – Lionel Blanchet – Analytica Chimica Acta

More Microbes

Cultural isolation of spore-forming bacteria in human feces using bile acids – Masaru Tanaka – Scientific Reports

Bed bugs shape the indoor microbial community composition of infested homes – Madhavi L. Kakumanu – Science of The Total Environment