It’s been a while, but its time to highlight some recent mycobiome articles!
Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities – Wu et al. – Microbiome
Gut mycobiota in immunity and inflammatory disease – Li et al. – Immunity
Response to fungal dysbiosis by gut-resident CX3CR1(+) mononuclear phagocytes aggravates allergic airway disease.- Li et al. – Cell Host Microbe.
Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans. – Bacher et al. – Cell.
Prevalence and diversity of filamentous fungi in the airways of cystic fibrosis patients – a Dutch, multicentre study. – Engle et al. – J Cyst Fibros.
Early gut mycobiota and mother-offspring transfer. – Schei – Microbiome
Fungi form interkingdom microbial communities in the primordial human gut that develop with gestational age. – Willis et al – FASEB J.
Investigating colonization of the healthy adult gastrointestinal tract by fungi. – Auchtung et al. – mSphere.
CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi. – Leonardi et al. – Science.
Commensal Candida albicans positively calibrates systemic Th17 immunological responses. – Shao et al – Cell Host Microbe.
Macrophages maintain epithelium integrity by limiting fungal product absorption. – Chikina et al. – Cell.
Fungal symbionts produce prostaglandin E2 to promote their intestinal colonization. – Tan et al. – Front Cell Infect Microbiol.
The fungal mycobiome promotes pancreatic oncogenesis via activation of MBL. – Aykut et al – Nature.
Fungal microbiota dysbiosis in IBD. – Sokol et al – Gut.
Malassezia is associated with Crohn’s disease and exacerbates colitis in mouse models. – Limon et al – Cell Host Microbe.
Macrophage interactions with fungi and bacteria in inflammatory bowel disease. – Leonardi et al. – Curr Opin Gastroenterol.
Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis. – Lemoinne et al – Gut
Intestinal fungi contribute to development of alcoholic liver disease. – Yang et al – J Clin Invest.
The gut mycobiome of healthy mice is shaped by the environment and correlates with metabolic outcomes in response to diet – Mims and Al Abdallah et al. – Communications Biology
Profound mycobiome differences between segregated mouse colonies do not influence Th17 responses to a newly introduced gut fungal commensal. – Doron et al. – Fungal Genet Biol.
Season, age, and sex affect the fecal mycobiota of free-ranging Tibetan macaques (Macaca thibetana). – Sun et al – Am J Primatol.
Altered immunity of laboratory mice in the natural environment is associated with fungal colonization. – Yeung et al – Cell Host Microbe.
The fungal frontier: a comparative analysis of methods used in the study of the human gut mycobiome. – Huseyin et al. – Front Microbiol.
MetaEuk—sensitive, high-throughput gene discovery, and annotation for large-scale eukaryotic metagenomics – Karen et al. – Microbiome
Accurate and sensitive detection of microbial eukaryotes from whole metagenome shotgun sequencing – Lind et al – Microbiome
Tiara: Deep learning-based classification system for eukaryotic sequences – Karlicki et al – bioRxiv.org
~ Kent Willis, MD