Good morning everyone. Today’s digest will cover recent studies focusing on the diet derived changes in the gut microbiome, the role of gut microbiome on brain health, inflammatory responses, autism, cystic fibrosis, hepatic steatosis using animal experiments, and reviews highlight the tumor genomics along with the microbiome and secretome as a new strategy in colorectal cancer. Enjoy reading.

General microbiome

Review: Is microbiome a target for the management of allergy associated diseases in children? – Ribaldone DG – European Review for Medical and Pharmacological Sciences

Review: Integrating tumor genomics into studies of the microbiome in colorectal cancer – Michael B Burns – Gut Microbes

Gut microbiome

Assessing the in vivo data on low/no-calorie sweeteners and the gut microbiota – Alexandra R.Lobach – Food and Chemical Toxicology

Review: Analysing the Secretome of Gut Microbiota as the Next Strategy For Early Detection of Colorectal Cancer – Putri‐Intan‐Hafizah Megat Mohd Azlan – Proteomics

Review: Bottoms up: the role of gut microbiota in brain health – Nina Radisavljevic – Environmental Microbiology

Treponema species enrich the gut microbiota of traditional rural populations but are absent from urban individuals – E. Angelakis – New Microbes and New Infections

Comparative Microbiome Signatures and Short-Chain Fatty Acids in Mouse, Rat, Non-human Primate, and Human Feces – Ravinder Nagpal – Frontiers in Microbiology

Synergistic convergence of microbiota-specific systemic IgG and secretory IgA – Jehane Fadlallah – The Journal of Allergy and Clinical Immunology

Water and extremophile microbiome

Microbial community composition and diversity in the Indian Ocean deep sea REY-rich muds – Shuyan Wang – PLOS One

Animal experiments

Following spinal cord injury, PDE4B drives an acute, local inflammatory response and a chronic, systemic response exacerbated by gut dysbiosis and endotoxemia – Scott A.Myer – Neurobiology of Disease

The Acute Influence of Acid Suppression with Esomeprazole on Gastrointestinal Microbiota and Brain Gene Expression Profiles in a Murine Model of Restraint Stress – RobertMacLaren – Neuroscience

Microbial communities in swine lungs and their association with lung lesions – Tao Huang – Microbial Biotechnology

Report: Gut microbial compositions mirror caste‐specific diets in a major lineage of social insects – Saria Otani – Environmental Microbiology Reports

Diet‐Induced Dysbiosis and Genetic Background Synergize With Cystic Fibrosis Transmembrane Conductance Regulator Deficiency to Promote Cholangiopathy in Mice – Dominique Debray – Hepatology Communications

The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism – Fang Liu – Molecular Autism

Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice – Ning Jia – Nutritiion and Metabolism

Isolated Rearing at Lactation Increases Gut Microbial Diversity and Post-weaning Performance in PigsIsolated Rearing at Lactation Increases Gut Microbial Diversity and Post-weaning Performance in Pigs – Tsungcheng Tsai – Frontiers in Microbiology

Echinococcus granulosus Infection Results in an Increase in Eisenbergiella and Parabacteroides Genera in the Gut of Mice – Jianling Bao – Frontiers in Microbiology

Bioinformatics

Evaluation of metabolite-microbe correlation detection methods – YijunYou – Analytical Biochemistry

Microbes in News

Gut bacteria link to immunotherapy sparks interest – Brian Owens – Nature Biotechnology